Low percentages of regulatory T cells in common variable immunodeficiency (CVID) patients with autoimmune diseases and its association with increased numbers of CD4+CD45RO+ T and CD21low B cells.

CONCLUSIONS: Our results showed that 39% of patients with CVID had AI and reduced Tregs populations. Research in this area might provide noteworthy data to better understand immune dysfunction and dysregulation related to CVID.
PMID: 31103252 [PubMed - as supplied by publisher]

Source: Allergologia et Immunopathologia - May 14, 2019 Category: Allergy & Immunology Authors: López-Herrera G, Segura-Méndez NH, O'Farril-Romanillos P, Nuñez-Nuñez ME, Zarate-Hernández MC, Mogica-Martínez D, Yamazaki-Nakashimada MA, Staines-Boone AT, Santos-Argumedo L, Berrón-Ruiz L Tags: Allergol Immunopathol (Madr) Source Type: research