Pharmacokinetic changes and therapeutic drug monitoring of lamotrigine during pregnancy

ConclusionsThe pharmacokinetic changes in LTG during pregnancy displayed marked interpatient variation. TDM can support a rational treatment plan for LTG use during pregnancy. We recommend regular monitoring of LTG serum concentrations from prepregnancy to postpartum.

Source: Brain and Behavior - May 17, 2019 Category: Neurology Authors: Ye Ding, Xiaoping Tan, Shuo Zhang, Yang Guo Tags: ORIGINAL RESEARCH Source Type: research