Bone marrow-liver-thymus (BLT) immune humanized mice as a model to predict cytokine release syndrome.

This study demonstrates that BLT-humanized mice are capable of experiencing CRS, and could be used to screen biologics for this adverse event to enhance patient safety. PMID: 31082370 [PubMed - as supplied by publisher]
Source: Translational Research : the journal of laboratory and clinical medicine - Category: Laboratory Medicine Authors: Tags: Transl Res Source Type: research