Gluconate suppresses seizure activity in developing brains by inhibiting CLC-3 chloride channels

Neonatal seizures are different from adult seizures, and many antiepileptic drugs that are effective in adults often fail to treat neonates. Here, we report that gluconate inhibits neonatal seizure by inhibiti...

Source: Molecular Brain - May 15, 2019 Category: Neuroscience Authors: Zheng Wu, Qingwei Huo, Liang Ren, Fengping Dong, Mengyang Feng, Yue Wang, Yuting Bai, Bernhard L üscher, Sheng-Tian Li, Guan-Lei Wang, Cheng Long, Yun Wang, Gangyi Wu and Gong Chen Tags: Research Source Type: research