Family of neural wiring receptors in bilaterians defined by phylogenetic, biochemical, and structural evidence [Biochemistry]
The evolution of complex nervous systems was accompanied by the expansion of numerous protein families, including cell-adhesion molecules, surface receptors, and their ligands. These proteins mediate axonal guidance, synapse targeting, and other neuronal wiring-related functions. Recently, 32 interacting cell surface proteins belonging to two newly defined families of the Ig...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Shouqiang Cheng, Yeonwoo Park, Justyna D. Kurleto, Mili Jeon, Kai Zinn, Joseph W. Thornton, Engin Ozkan Tags: Biological Sciences Source Type: research