F95. Effect of HLA Alleles on Suicide Attempts and Chronic Pain in Women

Women have higher rates of suicide attempts (SA). A prominent risk factor for SA is chronic pain (CP), which is also more common in women. Immune dysfunction is associated with both conditions. An individual ’s immune response is shaped, in part, by the polymorphic Human Leukocyte Antigen (HLA) locus, which has been implicated widely in major psychiatric disorders. The goal of this study was to identify common HLA genotypes associated with both SA and CP.

Source: Biological Psychiatry - May 13, 2019 Category: Psychiatry Authors: Seyma Katrinli, Adriana Lori, Bekh Bradley, Tanja Jovanovic, Kerry Ressler, Alicia Smith Source Type: research