The Neurorestorative Benefit of GW3965 Treatment of Stroke in Mice [Original Contributions]

Conclusions—
These data indicate, for the first time, that GW3965 promotes synaptic protein expression and axonal growth and increases vascular remodeling, which may contribute to improvement of functional outcome after stroke. Increasing Angiopoietin-1/Tie2 signaling activity may play an important role in GW3965-induced brain plasticity and neurological recovery from stroke.

Source: Stroke - December 24, 2012 Category: Neurology Authors: Cui, X., Chopp, M., Zacharek, A., Cui, Y., Roberts, C., Chen, J. Tags: Pathology of Stroke, Other Stroke Treatment - Medical, Transient Ischemic Attacks Original Contributions Source Type: research