Nipah virus: Age and breathing difficulties increase the risk of disease spread

(Institut Pasteur) Nipah virus has been identified as an emerging infectious disease that may cause severe epidemics in the near future. Researchers from the Institut Pasteur, CNRS, icddr,b, and Johns Hopkins Bloomberg School of Public Health, just showed that adult cases with respiratory symptoms transmit the virus to more individuals than other cases, and might therefore be targeted for interventions when the isolation of all suspected Nipah cases is not possible. This research paves the way to more efficient control measures.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news

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This study was a step towards understanding the CoV circulation in Indian bats. Detection of potentially pathogenic CoVs in Indian bats stresses the need for enhanced screening for novel viruses in them. One Health approach with collaborative activities by the animal health and human health sectors in these surveillance activities shall be of use to public health. This would help in the development of diagnostic assays for novel viruses with outbreak potential and be useful in disease interventions. Proactive surveillance remains crucial for identifying the emerging novel viruses with epidemic potential and measures for ri...
Source: Indian J Med Res - Category: Research Authors: Tags: Indian J Med Res Source Type: research
By Anis Chowdhury and Jomo Kwame SundaramSYDNEY and KUALA LUMPUR, Apr 9 2020 (IPS) Within weeks, the Covid-19 epidemic was classified by the World Health Organization (WHO) as an epidemic of international significance, triggering a pre-agreed WHO response. By the end of the first week of April, more than 1.3 million people had been confirmed as infected, with over 65,000 deaths across the world. Anis Chowdhury Many governments of developing, especially poor countries are unsure what to do, fearing the likely economic consequences of the ‘lockdowns’ increasingly adopted by Western economies. Indeed, lockdowns m...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Asia-Pacific Civil Society Development & Aid Economy & Trade Featured Global Headlines Health Humanitarian Emergencies TerraViva United Nations Jomo Kwame Sundaram & Anis Chowdhury Source Type: news
This article describes elements of design of such unit (e.g., space, infection control, waste disposal, safety of healthcare workers, partners to be involved in design and plan) which can be adapted to the context of either a new construction or makeshift construction on top of an existing structure. In view of a potential epidemic of COVID-19, specific requirements to handle it are also given. PMID: 32202258 [PubMed - as supplied by publisher]
Source: Indian J Med Res - Category: Research Authors: Tags: Indian J Med Res Source Type: research
As the world grapples with the COVID-19 pandemic, some experts say India — a country of more than 1.3 billion people — likely has many more cases than the conservative numbers currently being reported. The outbreak of the new coronavirus, which causes COVID-19, began in China and has since infected more than 124,000 people across more than 110 countries and territories around the world. More than 4,500 people worldwide have died after being infected with COVID-19. India has conducted nearly 5,000 COVID-19 tests so far, according to the World Health Organization, which says that the “country is responding ...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized COVID-19 Explainer Source Type: news
Research in the last decade has uncovered many new paramyxoviruses, airborne agents that cause epidemic diseases in animals including humans. Most paramyxoviruses enter epithelial cells of the airway using sialic acid as a receptor and cause only mild disease. However, others cross the epithelial barrier and cause more severe disease. For some of these viruses, the host receptors have been identified, and the mechanisms of cell entry have been elucidated. The tetrameric attachment proteins of paramyxoviruses have vastly different binding affinities for their cognate receptors, which they contact through different binding s...
Source: Journal of Biological Chemistry - Category: Chemistry Authors: Tags: JBC Reviews Source Type: research
Conclusion: The rapid spread of infection uncovered the miserable state of health care system in implementing infection control measures. The case fatality and the socio-economic burden warrant developing appropriate treatments, vaccines and diagnostics.
Source: Journal of Global Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research
This article describes elements of design of such unit (e.g., space, infection control, waste disposal, safety of healthcare workers, partners to be involved in design and plan) which can be adapted to the context of either a new construction or makeshift construction on top of an existing structure. In view of a potential epidemic of COVID-19, specific requirements to handle it are also given. PMID: 32362643 [PubMed - in process]
Source: The Indian Journal of Medical Research - Category: Biomedical Science Authors: Tags: Indian J Med Res Source Type: research
They are considered the probable source of the coronavirus outbreak spreading from China. It turns out that they may have an immune system that lets them coexist with many disease-causing viruses.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Bats Viruses Epidemics Coronavirus (2019-nCoV) Marburg Virus Nipah Virus Hendra Virus SARS (Severe Acute Respiratory Syndrome) MERS (Middle East Respiratory Syndrome) Immune System Cell Host and Microbe (Journal) EcoHealth Alliance Source Type: news
Abstract Launched at Davos in January 2017 with funding from sovereign investors and philanthropic institutions, the Coalition for Epidemic Preparedness Innovations (CEPI) is an innovative partnership between public, private, philanthropic, and civil organisations whose mission is to stimulate, finance and co-ordinate vaccine development against diseases with epidemic potential in cases where market incentives fail. As of December 2019, CEPI has committed to investing up to $706 million in vaccine development. This includes 19 vaccine candidates against its priority pathogens (Lassa fever virus, Middle East respir...
Source: Vaccine - Category: Allergy & Immunology Authors: Tags: Vaccine Source Type: research
Condition:   Nipah Virus Infection Interventions:   Biological: HeV-sG-V;   Biological: Normal Saline Placebo Sponsors:   Profectus BioSciences, Inc.;   PATH;   Coalition for Epidemic Preparedness Initiative (CEPI);   Cincinnati Children's Hospital Medical Center (CCHMC) Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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