The Beneficial effects of Mediterranean diet over low-fat diet may be mediated by decreasing hepatic fat content

Beyond total body fat content, fat distribution, both within adipose tissue depots and in ectopic fat deposits, is increasingly shown to determine obesity-related health impact [1,2]. Visceral adipose tissue (VAT), due to its unique anatomical location, releases free fatty acids (FFA) and adipokines to the liver via the portal vein.Previous studies have demonstrated the inter-relationship between VAT and hepatic fat content (HFC), and indeed, increases in HFC were associated with similar metabolic abnormalities as observed for increases in VAT [3,4].

Source: Journal of Hepatology - May 6, 2019 Category: Gastroenterology Authors: Yftach Gepner, Ilan Shelef, Oded Komy, Noa Cohen, Dan Schwarzfuchs, Nitzan Bril, Michal Rein, Dana Serfaty, Shira Kenigsbuch, Hila Zelicha, Anat Yaskolka Meir, Lilac Tene, Avital Bilitzky, Gal Tsaban, Yoash Chassidim, Benjamin Sarusy, Uta Ceglarek, Joachi Source Type: research