Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells

DNA methyltransferases (DNMTs) are epigenetic enzymes involved in embryonic development, cell differentiation, epithelial to mesenchymal transition, and control of gene expression, whose overexpression or enha...

Source: Clinical Epigenetics - May 6, 2019 Category: Research Authors: Clemens Zwergel, Michael Schnekenburger, Federica Sarno, Cecilia Battistelli, Maria Cristina Manara, Giulia Stazi, Roberta Mazzone, Rossella Fioravanti, Christina Gros, Fr édéric Ausseil, Cristina Florean, Angela Nebbioso, Raffaele Strippoli, Toshikazu Tags: Research Source Type: research