Angiotensin II Triggers Autophagy and Apoptosis in PC12 Cell Line: An in vitro Alzheimer's Disease Model.

CONCLUSIONS: Taken together, our study strengthen the crucial function of Ang II/AT1R axis in the pathogenesis of AD in vitro. These findings have deepened our understanding on the role of Ang II in the pathogenesis of AD and support the use of AT1R antagonists for the treatment of this devastating neurodegenerative disease. PMID: 31054884 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31054884?dopt=Abstract

Source: Brain Research - May 1, 2019 Category: Neurology Authors: Tian M, Lin X, Wu L, Lu J, Zhang Y, Shi J Tags: Brain Res Source Type: research