Clinical utility of genetic diagnosis for sporadic and hereditary medullary thyroid carcinoma.

In conclusions RET genetic screening allows the identification of the hereditary/sporadic nature of MTC and of a relevant percentage of hidden familial MTC. Furthermore, it favors the early diagnosis of MTC in RET positive subjects. RET positive patients and no clinical evidence of MTC can be followed and surgical treatment can be delayed. Finally RET negative relatives do not need to be further monitored. PMID: 31053251 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31053251?dopt=Abstract

Source: Annales d'Endocrinologie - April 10, 2019 Category: Endocrinology Authors: Elisei R, Bottici V, Cappagli V, Ramone T, Tacito A, Ciampi R, Romei C Tags: Ann Endocrinol (Paris) Source Type: research