Effects of Boschnaloside from Boschniakia rossica on dysglycemia and islet dysfunction in severely diabetic mice through modulating the action of glucagon-like peptide-1.

ConclusionIt appears that bochnaloside at oral dosage greater than 150 mg/kg/day exerts antidiabetic effects in vivo through modulating the action of GLP-1.Graphic AbstractBoschnaloside is the major constituent from Boschniakia rossica, an herb for tonifying kidney and improving impotence. Boschnaloside supplement attenuates diabetic symptoms and islet dysfunction in severely diabetic db/db mice. Underlying mechanism of actions involves in modulating the action of glucagon-like peptide-1.
Source: Phytomedicine - Category: Drugs & Pharmacology Source Type: research