Soluble TNF-R1, VEGF and other cytokines as markers of disease activity in systemic lupus erythematosus and lupus nephritis.
CONCLUSION: These results indicate that for active LN, sTNF-R1 could be a useful serum cytokine marker, with potential for VEGF in the urine. This study has confirmed the ability of the multiplex bead technique to detect cytokines in a good analytical range, including very low and high levels, in both serum and urine. Combining serum and urine markers provided additional sensitivity in distinguishing active from inactive LN.
PMID: 31046570 [PubMed - as supplied by publisher]
Source: Lupus - Category: Rheumatology Authors: Adhya Z, El Anbari M, Anwar S, Mortimer A, Marr N, Karim MY Tags: Lupus Source Type: research