Amitriptyline for neuropathic pain and fibromyalgia in adults

Source: Cochrane Area: Evidence > Drug Specific Reviews Background   Amitriptyline is a tricyclic antidepressant that is widely used to treat chronic neuropathic pain (pain due to nerve damage) and fibromyalgia, and is recommended in many guidelines. These types of pain can be treated with antidepressant drugs in doses below those at which the drugs act as antidepressants.         Objectives   To assess the analgesic efficacy of amitriptyline for chronic neuropathic pain and fibromyalgia.To assess the adverse events associated with the clinical use of amitriptyline for chronic neuropathic pain and fibromyalgia.         Search methods     We searched CENTRAL, MEDLINE, and EMBASE to September 2012, together with reference lists of retrieved papers, previous systematic reviews, and other reviews; we also used our own handsearched database for older studies.       ...
Source: NeLM - Drug Specific Reviews - Category: Drugs & Pharmacology Source Type: news