Quantification of 1D, a novel derivative of curcumin with potential antitumor activity, in rat plasma by liquid chromatography-tandem mass spectrometry: application to a pharmacokinetic study in rats.

CONCLUSIONS: Results demonstrated that 1 D displayed favourable pharmacokinetic properties for further in vivo pharmacologic evaluation, which could be facilitated by the validated LC-MS/MS method. PMID: 31017510 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/31017510?dopt=Abstract

Source: Pharmaceutical Biology - April 26, 2019 Category: Drugs & Pharmacology Tags: Pharm Biol Source Type: research