ERK5 Regulates Glucose-Induced Increased Fibronectin Production in the Endothelial Cells and in the Retina in Diabetes [Retina]

Conclusions. Our experiments demonstrated a novel mechanism of glucose-induced increased FN production in diabetic retinopathy, which is mediated through decreased ERK5 signaling.

http://www.iovs.org/cgi/content/full/53/13/8405?rss=1

Source: Investigative Ophthalmology - December 19, 2012 Category: Opthalmology Authors: Wu, Y., Feng, B., Chen, S., Chakrabarti, S. Tags: Retina Source Type: research