Progression of anal intraepithelial neoplasia in HIV-positive individuals: predisposing factors

ConclusionsIn our large cohort of HIV-positive patients treated without high resolution anoscopy the rate of progression was low.   Most notably, visible lesions at initial presentation and CD4 count when lower were associated with progression. Initial surgical pathology of anal condylomata was associated with progression, while high-risk serotypes correlated with regression or stability. Identification of risk factors has important implications concerning postoperative surveillance and counseling of HIV-positive patients with anal condylomata/ anal dysplasia.
Source: Techniques in Coloproctology - Category: Surgery Source Type: research