MRE could measure brain function dramatically faster

U.S. and European researchers could be on the brink of advancing the measurements...Read more on AuntMinnie.comRelated Reading: Steatosis complicates MR elastography for liver fibrosis 10 top tips on best use of MR enterography in small bowel MRE delves into traumatic brain injury MR elastography detects liver disease in obese children
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

Related Links:

AbstractObjectiveTo evaluate the association between high uric acid (UA), reduced estimated glomerular filtration rate (eGFR), and non-alcoholic fatty liver disease (NAFLD) in outpatient children and adolescents with overweight (OW) or obesity (OB).MethodsAnthropometric, biochemical, hepatic ultrasound and eGFR data were available from 2565 young people with OW/OB (age 5 –18 years). eGFR was calculated using the Schwartz’s bedside formula and reduced eGFR (ReGFR+) was defined by a value  
Source: Journal of Endocrinological Investigation - Category: Endocrinology Source Type: research
Authors: Marjot T, Moolla A, Cobbold JF, Hodson L, Tomlinson JW Abstract Non-alcoholic fatty liver disease (NAFLD) is a spectrum of disease, extending from simple steatosis, through to inflammation and fibrosis with a significant risk for the development of cirrhosis. It is highly prevalent and is associated with significant adverse outcomes both through liver-specific morbidity and mortality, but perhaps more importantly, through adverse cardiovascular and metabolic outcomes. It is tightly associated with type 2 diabetes and obesity and both of these conditions drive progressive disease towards the more advanced s...
Source: Endocrine Reviews - Category: Endocrinology Tags: Endocr Rev Source Type: research
(NAFLD) is a global health problem, with an estimated prevalence of 30% among adults in industrialized countries, and associated with obesity and type 2 diabetes mellitus. NAFLD is defined histologically and represents a spectrum from simple steatosis to steatohepatitis, fibrosis and cirrhosis. Hepatic triglyceride droplet accumulation is considered the first feature in the natural history; in some patients, this is associated with inflammation and fibrosis, through the interaction of environmental and host factors.
Source: Medicine - Category: Internal Medicine Authors: Tags: Common european liver disorders Source Type: research
Publication date: Available online 17 October 2019Source: Trends in Endocrinology &MetabolismAuthor(s): Daniela Stols-Gonçalves, G. Kees Hovingh, Max Nieuwdorp, Adriaan G. HolleboomThe prevalence of non-alcoholic fatty liver disease (NAFLD) is strongly increasing and may put patients at increased risk for atherosclerotic cardiovascular disease (asCVD). Both disease phenotypes often co-occur, in the case of obesity, insulin resistance, diabetes mellitus type 2, and the metabolic syndrome. We explore the pathogenesis of NAFLD, the epidemiology of asCVD in NAFLD patients, shared drivers of both phenotypes, and fact...
Source: Trends in Endocrinology and Metabolism - Category: Endocrinology Source Type: research
Recent studies have identified a genetic variant rs641738 near two genes encoding membrane boundO-acyltransferase domain-containing 7 (MBOAT7) and transmembrane channel-like 4 (TMC4) that associate with increased risk of non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), alcohol-related cirrhosis, and liver fibrosis in those infected with viral hepatitis1-7. Based on hepatic expression quantitative trait loci analysis it has been suggested thatMBOAT7 loss of function promotes liver disease progression1-7, but this has never been formally tested. Here we show thatMboat7 loss, but notTmc4, in mi...
Source: eLife - Category: Biomedical Science Tags: Human Biology and Medicine Source Type: research
(CNN) — Americans spent $1.4 billion on the most popular brands of children’s fruit drinks and flavored waters last year. Yet according to nutritional guidelines, none of the drinks were healthy. Why would loving parents do this? Perhaps because US beverage companies spent $20.7 million to advertise fun, fruity drinks with added sugars to families in 2018, according to Children’s Drink Facts 2019, a new report from the University of Connecticut’s Rudd Center for Food Policy and Obesity. “I know that parents want their children to be healthy, but the sweetened drink market is just incredibly co...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Health News Syndicated CBSN Boston CNN juice Source Type: news
Non-alcoholic fatty liver disease (NAFLD) is common and related to obesity and insulin resistance. Iron metabolism is impaired in obese individuals and iron deficiency has been associated with physical inactivity. We investigated whether iron bioavailability is reduced in patients with NAFLD and contributes to reduced cardiorespiratory fitness.
Source: Clinical Gastroenterology and Hepatology - Category: Gastroenterology Authors: Source Type: research
CONCLUSION: Our study reinforces the role of older age, obesity and hepatomegaly as predictors of fatty liver disease. These variables should be considered in the assessment of fatty changes in the livers of potential liver donors.
Source: Clinics - Category: General Medicine Source Type: research
In this study, ICR male mice were fed a high-fat diet (HFD) in vivo and the AML12 cells were treated with palmitic acid (PA) in vitro. We explore the protective effect and potential mechanism of Chinese Herbal Formula (CHF03) against NAFLD by HE staining, transmission Electron Microscopy assay, Western blotting, and gene expression. In vivo, oxidative stress markers (GSH, GSH-px, MDA, SOD, and CAT) confirmed that CHF03 alleviated oxidative stress and abundance of NF-κB proteins indicating a reduction in inflammation and oxidative stress. The lower protein abundance of ACACA and FASN indicated a preventive effect on l...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
This study aimed to investigate prevalence and risk factors of biopsy proven NAFLD in a cluster of healthy non-obese and lean individuals.Methods and MaterialsIn a retrospective study, adult (> 18 years) apparently healthy individuals who had donated liver to pediatric patients between July 2012 and October 2018 were included. Non-obese and lean individuals were defined as BMI 
Source: Clinics and Research in Hepatology and Gastroenterology - Category: Gastroenterology Source Type: research
More News: Brain | Children | Eating Disorders & Weight Management | Liver | Liver Disease | Neurology | Obesity | Radiology | Urology & Nephrology