Scientists 3-D-printed a tiny human heart. They hope it can revolutionize transplants.

Scientists created an artificial heart with human tissue.
Source: Washington Post: To Your Health - Category: Consumer Health News Authors: Source Type: news

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Human-induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) have shed great light on cardiac regenerative medicine and specifically myocardial repair in heart failure patients. However, the treatment...
Source: Stem Cell Research and Therapy - Category: Stem Cells Authors: Tags: Research Source Type: research
ConclusionsWe found a significantly increased five-year survival rate for heart-kidney transplant recipients compared to isolated heart transplant recipients with renal impairment. Lack of improvement in five-year post-operative outcomes for heart-kidney recipients in the setting of higher risk pre-transplant clinical characteristics suggests decreased selectivity regarding heart-kidney recipients. Continued scrutiny and evaluation of post-operative outcomes are required to ensure just and appropriate utilization of organs.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
Authors: Chiba Y, Fukushima A, Nakao M, Kobayashi Y, Ishigaki T, Tenma T, Kamiya K, Shingu Y, Ooka T, Matsui Y, Anzai T Abstract A 23-year-old man had progressive muscle weakness and Emery-Dreifuss muscular dystrophy (EDMD) due to a LMNA (lamin A/C) mutation. Congestive heart failure diagnosed at 19 years of age. Maximal drug treatment/cardiac resynchronization failed to improve the cardiac function. He was therefore hospitalized due to heart failure. Despite extracorporeal membrane oxygenation, he developed severe right heart dysfunction and died (multiple organ failure). A cardiac lesion's presence determines the...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
Conditions:   Heart Transplant Infection;   CMV Infection Intervention:   Diagnostic Test: ELISPOT IFN-γ assay Sponsors:   Hospital Universitari de Bellvitge;   Instituto de Salud Carlos III;   Sociedad Española de Cardiología Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Heart Transplant Infection;   CMV Infection Intervention:   Diagnostic Test: ELISPOT IFN-γ assay Sponsors:   Hospital Universitari de Bellvitge;   Instituto de Salud Carlos III;   Sociedad Española de Cardiología Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Heart Transplant Infection;   CMV Infection Intervention:   Diagnostic Test: ELISPOT IFN-γ assay Sponsors:   Hospital Universitari de Bellvitge;   Instituto de Salud Carlos III;   Sociedad Española de Cardiología Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conditions:   Heart Transplant Infection;   CMV Infection Intervention:   Diagnostic Test: ELISPOT IFN-γ assay Sponsors:   Hospital Universitari de Bellvitge;   Instituto de Salud Carlos III;   Sociedad Española de Cardiología Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Liver biopsy is the gold standard for diagnosing liver disease in patients undergoing evaluation for heart transplant. Obtaining an accurate assessment of the liver is crucial, as it predicts outcomes of heart transplantation. Transabdominal liver biopsy increases the risk of bleeding and can be dangerous due to the limited cardiac reserve of these patients, therefore transvenous approaches are preferable. Studies show that patients with congestive hepatopathy have heterogeneous involvement of the liver.
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Scientific Session 22 Source Type: research
This study reports on the largest single-center experience of lung transplantation for adult and pediatric CF patients. It also highlights the evolution of practice and outcomes over time.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: Original Clinical Science Source Type: research
This report was marred with ethical controversy. It was argued that reanimation of the donor heart invalidates the donor circulatory death determination, since circulatory death in the United States is defined by irreversible cardiac arrest. The resulting legal ambiguity stifled further DCD heart transplantation activity in America.2 However, the introduction of ex-situ heart perfusion and donor normothermic regional perfusion for functional assessment as well as further development of the relevant legal and ethical frameworks allowed pioneers in Australia and the United Kingdom to resume transplanting adult DCD hearts.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: Research Correspondence Source Type: research
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