Best supplements for arthritis: Three vitamin supplements to help alleviate joint pain

BEST SUPPLEMENTS for arthritis: Arthritis is a lifelong condition, but including the right vitamins in your diet can help improve symptoms and prevent the joint problem from worsening. These three vitamin supplements can help alleviate arthritis.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news

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Publication date: Available online 15 April 2019Source: Best Practice &Research Clinical RheumatologyAuthor(s): Diederik De Cock, Kimme HyrichAbstractRheumatoid arthritis (RA) is a chronic inflammatory condition that can result in pain and functional disability. It is also associated with an increased occurrence of comorbidities, including an increased risk of certain cancers such as lung cancer and lymphoma. The aetiopathogenesis of this increased cancer risk is likely multifactorial and includes shared risk factors as well as chronic inflammation. There is also a concern that the treatment for RA itself may increase ...
Source: Best Practice and Research Clinical Rheumatology - Category: Rheumatology Source Type: research
Intestinal Epithelial Cells-Derived Hypoxia-Inducible Factor-1α Is Essential for the Homeostasis of Intestinal Intraepithelial Lymphocytes Lihua Sun1, Teming Li1, Hanlin Tang1, Kun Yu1, Yuanhang Ma1, Min Yu1, Yuan Qiu1, Pengyuan Xu2, Weidong Xiao1* and Hua Yang1* 1Department of General Surgery, Xinqiao Hospital, Third Military Medical University, Chongqing, China 2Department of Gastrointestinal Surgery, The Second Affiliated Hospital of Kunming Medical University, Kunming, China Hif-1α is a master regulator which involved in the transcriptional regulation of anti-inflammatory or cellular responding to h...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Zhi-Chao Hu1,2,3†, Zu-Cheng Luo1,2,3†, Bing-Jie Jiang1,2,3†, Xin Fu1,2,3, Jiang-Wei Xuan1,2,3, Xiao-Bin Li1,2,3, Yu-Jie Bian1,2,3, Wen-Fei Ni1,2,3* and Ji-Xin Xue1,2,3* 1Department of Orthopaedics, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, China 2The Second School of Medicine, Wenzhou Medical University, Wenzhou, China 3Bone Research Institute, The Key Orthopaedic Laboratory of Zhejiang Province, Wenzhou, China Osteoarthritis (OA), defined as a long-term progressive joint disease, is characterized by cartilage impairment and ...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Intervertebral disc degeneration (IDD) is a major contributor to back, neck, and radicular pain, and the treatment of IDD is costly and relatively ineffective. Dysregulation of microRNAs (miRNAs) has been repo...
Source: Arthritis Research and Therapy - Category: Rheumatology Authors: Tags: Research article Source Type: research
To investigate the association between knee pain and risk factors including low back pain and to develop a score to predict new knee pain in an older population, using population-based longitudinal cohort data.
Source: Arthritis Research and Therapy - Category: Rheumatology Authors: Tags: Research article Source Type: research
In this study, we found that senescent chondrocytes isolated from OA patients secrete more EVs compared with nonsenescent chondrocytes. These EVs inhibit cartilage ECM deposition by healthy chondrocytes and can induce a senescent state in nearby cells. We profiled the miR and protein content of EVs isolated from the synovial fluid of OA joints from mice with SnCs. After treatment with a molecule to remove SnCs, termed a senolytic, the composition of EV-associated miR and protein was markedly altered. The senolytic reduced OA development and enhanced chondrogenesis, and these were attributable to several specific differenti...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Caito Foods is voluntarily recalling fresh cut watermelon, fresh cut honeydew melon, fresh cut cantaloupe and fresh cut mixed fruit containing one of these melons, produced at the Caito Foods facility in Indianapolis because these products have the potential to be contaminated with Salmonella Carrau, an organism which can cause serious and sometimes fatal infections in young children, frail or elderly people, and others with weakened immune systems. Healthy persons infected with Salmonella often experience fever, diarrhea (which may be bloody), nausea, vomiting and abdominal pain. In rare circumstances, infection with Salm...
Source: Food and Drug Administration - Category: Food Science Source Type: news
“Come back when you’ve lost 40 pounds.” That’s something obese patients have heard often when being evaluated for a hip or knee replacement for severe arthritis. And sometimes the recommendation is to lose even more — 50, 75, or even 100 pounds… as if that’s an easy or realistic prospect. As you might expect, patients hearing this often feel disappointed and disheartened. After all, most have already tried hard to lose weight with limited success. Their arthritis pain impairs their ability to exercise, and decreasing activity has contributed to their weight gain. So being told to ...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Arthritis Bones and joints Health Surgery Source Type: blogs
Conclusion This paper summarizes the current findings regarding the anti-colitis activity of plant-derived alkaloids and shows how these alkaloids exhibit significant and beneficial effects in alleviating colonic inflammation. These natural alkaloids are not only promising agents for IBD treatment but are also components for developing new wonder drugs. However, the underlying molecular mechanisms or toxicological evaluation of most plant-derived alkaloids still require much scientific research, and their actual efficacies for IBD patients have not been verified well in field research. Thus, further clinical trials to elu...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Conclusion Trochlear pain (trochleodynia) is becoming recognized as a set of disorders that can present in isolation or concomitantly with co-existing migraines, tension-type headaches, or other headache disorders, possibly explaining subpar symptom control in a small but significant number of individuals globally. Trochleodynia features unilateral periocular pain that may involve the ipsilateral hemicranium. Pain exacerbation occurs with trochlear palpation and supraduction of the affected eye especially in the adducted position. Trochleodynia may respond to oral NSAIDs if symptoms are mild and of recent onset. While ora...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
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