Child abuse, recurrent depression linked to similar changes in brain
(Reuters Health) - Abuse during childhood may cause physical changes to the human brain that in turn may render adults more vulnerable to depression, research suggests.
ConclusionMinimal preoperative factors are associated with nonresponse for women having surgery for endometriosis. The severity of pain experienced by women with endometriosis may be used to predict their response to surgery.
CONCLUSION: This meta-analysis suggests that depression in patients was associated with increased risk of developing ventricular arrhythmias, especially in patients with CHD. Cardiologists and psychiatrists should be alert to the risk of ventricular arrhythmia in patients with depression. Moreover, the antidepressant medications (e.g., tricyclic antidepressants and selective serotonin reuptake inhibitors) that could affect heart rate variability should be used carefully. . PMID: 30990407 [PubMed - as supplied by publisher]
Rates of depression and suicide are far higher in the rural US than in urban areas. Researchers at the University of New South Wales gave at-home brain stim to rural patients - but experts warn of dangers.
This study aims to investigate health-related quality of life (HRQOL) at baseline and at follow-up in older patients with cancer and to determine prognostic factors for HRQOL decline.MethodsA prospective Belgian multicentre (n = 22) study was performed. Patients ≥70 years with a malignant tumor and abnormal G8 (≤14/17) screening tool were included. Patients underwent geriatric assessment (GA) and HRQOL evaluation with follow up at three months. Uni- and multivariate regression models were performed to determine factors associated (p
ConclusionThis screening tool identified geriatric syndromes requiring attention in many patients with breast cancer presenting for medical oncology appointments. In oncology practice, need for referral networks to address geriatric syndromes should be assessed.
Conclusions: GHB-use but in particular GHB-induced comas, are associated with altered emotion identification and hippocampal functioning. Awareness campaigns are required to raise consciousness about the adverse effects of GHB-induced comas on affect regulation, despite the absence of subjective side effects.Eur Addict Res
Conclusions: Duloxetine can protect the brain against methamphetamine withdrawal-induced mood and motor disturbances and can also inhibit methamphetamine-induced cognitive impairment, possibly via cAMP/CREB/BDNF signaling pathway. PMID: 30993081 [PubMed]
Diagnosis of depression is infrequently recorded on older adults ’ patient notes, a survey of 27 acute hospitals across England has shown.
CONCLUSIONS: OCD is an under-treated public health problem that needs more attention in Greece and elsewhere. Provision of specialised mental health services should be a priority for publicly funded national health systems. Keypoints OCD is common in the general population of Greece with few sociodemographic associations apart from subjective financial difficulties. The comorbidity pattern of the full-blown syndrome versus the subthreshold obsessive-compulsive symptoms is similar and differs in magnitude in the expected way. Quality of life in OCD is greatly reduced especially when there is chronicity and/or comorbidity wi...
Conclusions: Pediatric OI patients showed deviations in the intestinal bacterial flora. The intestinal flora can serve as a novel therapeutic target for the mental health management of intractable pediatric OI patients. PMID: 30995366 [PubMed - in process]