Effect of tumor necrosis factor α on ability of SHED to promote osteoclastogenesis during physiological root resorption

In conclusion, inflammatory cytokine TNF-α appeared to activate NF-κB pathway to up-regulate expression of NF-κB, enhancing ability of SHED in promoting osteoclastogenesis via regulating RANKL/OPG expression.
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research