Genomic analysis offers roadmap for diagnosis and treatment of a high-risk leukemia

(St. Jude Children's Research Hospital) Acute erythroid leukemia (AEL) is a high-risk cancer with a dismal prognosis, uncertain genetic basis and controversy surrounding the diagnosis. That is changing, thanks to research led by St. Jude Children's Research Hospital that appears today in the journal Nature Genetics.The researchers completed the largest, most comprehensive genomic analysis yet of AEL and identified six age-related subgroups with distinct mutations and patterns of gene expression as well as treatment outcomes.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news