The role of autophagy in the overexpression of MUC5AC in patients with chronic rhinosinusitis.

CONCLUSIONS: In HNE-induced CRS, autophagy increases the secretion of MUC5AC by promoting the phosphorylation of JNK and c-Jun.
PMID: 30909132 [PubMed - as supplied by publisher]

Source: International Immunopharmacology - March 21, 2019 Category: Allergy & Immunology Authors: Ye Y, Zhao J, Ye J, Jiang X, Liu H, Xie Y, Zhang J, Luo Q Tags: Int Immunopharmacol Source Type: research