Interaction of antioxidant gene variants and susceptibility to Type 2 Diabetes Mellitus.

CONCLUSION: As the number of gene combinations increase, there is a rise in odds ratio showing disease risk, suggesting that gene-gene interaction plays an important role in T2DM susceptibility. Individuals who possess the GSTM1del, GSTT1del, GSTP1 105I/V(+313A/G), CAT-21A/T, SOD2+47C/T and GPx1+599C/T are at very high risk of developing T2DM. PMID: 30900957 [PubMed - as supplied by publisher]
Source: British Journal of Biomedical Science - Category: Laboratory Medicine Tags: Br J Biomed Sci Source Type: research