Spray drying OZ439 nanoparticles to form stable, water-dispersible powders for oral malaria therapy

OZ439 is a new chemical entity which is active against drug-resistant malaria and shows potential as a single-dose cure. However, development of an oral formulation with desired exposure has proved problematic...

Source: Journal of Translational Medicine - March 22, 2019 Category: Research Authors: Kurt D. Ristroph, Jie Feng, Simon A. McManus, Yingyue Zhang, Kai Gong, Hanu Ramachandruni, Claire E. White and Robert K. Prud ’homme Tags: Research Source Type: research