Promotion of Calcium/Calmodulin ‐Dependent Protein Kinase 4 by GLUT1‐Dependent Glycolysis in Systemic Lupus Erythematosus

ConclusionThe results of the study indicate that the activity of CaMK4 could be responsible for glycolysis, which contributes to the production of IL ‐17, and CaMK4 may contribute to aberrant expression of GLUT1 in T cells from patients with active SLE.

Source: Arthritis and Rheumatology - March 19, 2019 Category: Rheumatology Authors: Tomohiro Koga, Tomohito Sato, Kaori Furukawa, Shimpei Morimoto, Yushiro Endo, Masataka Umeda, Remi Sumiyoshi, Shoichi Fukui, Shin ‐ya Kawashiri, Naoki Iwamoto, Kunihiro Ichinose, Mami Tamai, Tomoki Origuchi, Hideki Nakamura, Atsushi Kawaka Tags: Brief Report Source Type: research