The Quest for the Culprit Responsible for Arteriovenous Fistula Maturation Failure

In this issue, Kubiak et  al. report on 562 patients with chronic kidney disease (CKD) undergoing single stage surgical creation of an autologous upper extremity arteriovenous fistula (AVF).1 This was actually a sub-study of the somewhat larger Haemodialysis Fistula Maturation Study, with the aim of testing the association between mineral metabolism markers (MMMs) and histology of vein samples obtained at AVF creation and also unassisted and overall clinical AVF maturation. MMMs included fibroblast growth factor-23, parathyroid hormone, calcium, phosphate, and the vitamin D metabolites 1,25(OH)2D, 24,25(OH)2D, 25(OH) D, and bioavailable 25(OH)D.
Source: European Journal of Vascular and Endovascular Surgery - Category: Surgery Authors: Tags: Invited Commentary Source Type: research