Bridging biophysics and neurology: aberrant phase transitions in neurodegenerative disease

Bridging biophysics and neurology: aberrant phase transitions in neurodegenerative diseaseBridging biophysics and neurology: aberrant phase transitions in neurodegenerative disease, Published online: 19 March 2019; doi:10.1038/s41582-019-0157-5In this Review, Nedelsky and Taylor review the evidence that disturbances in phase transition dynamics and the material properties of ribonucleoprotein granules underlie the pathogenesis of many neurodegenerative diseases, including forms of amyotrophic lateral sclerosis and frontotemporal dementia, among others.

Source: Nature Reviews Neurology - March 18, 2019 Category: Neurology Authors: Natalia B. Nedelsky J. Paul Taylor Source Type: research