Early Massive Pulmonary Embolism After Total Hip Arthroplasty in a Patient With Behcet Disease: A Case Report
We describe a woman with BD who presented with a massive bilateral pulmonary embolism 30 hours after total hip arthroplasty. The patient underwent surgical thrombectomy and venoarterial extracorporeal membrane oxygenation. Methotrexate was withheld 15 days before surgery and restarted on postoperative day 2. Immunosuppressive therapy, such as methotrexate, appears to be the most effective prophylactic treatment for venous thrombosis in patients with BD, whereas prophylaxis with low-molecular-weight heparin may be ineffective, as was the situation in our patient. Therefore, continuation of methotrexate perioperatively should be considered in patients with BD. Systematically performing preoperative deep vein thrombosis screening should be also considered. The patient also had diabetes mellitus treated with metformin and sitagliptin preoperatively.
Conclusion Our study provides novel evidence that EXE-induced antisenescence against metabolic distress in the hippocampus may be a key neuroprotective mechanism, preventing neuroinflammation and oxidative stress.
Purpose Low-attenuation muscle (LAM) area at mid-thigh, a computed tomography (CT)–derived index of intramuscular lipids, is associated with insulin resistance, obesity, and type 2 diabetes. The present study aimed at testing the hypothesis that changes in LAM area in trunk muscles from a single abdominal scan could provide relevant information to evaluate the effects of a lifestyle intervention without the use of a mid-thigh CT scan. Methods Cardiometabolic risk variables, including waist circumference, lipoprotein–lipid profile, glucose tolerance, and cardiorespiratory fitness, were assessed in a sample ...
This study investigated whether periodontal treatment might improve glycemic control in patients with chronic periodontitis and type 2 diabetes mellitus, and which modality offers most benefit.BMC Oral Health
CONCLUSIONS: LL-37 concentrations were highest in patients with T2DM+CP when compared with controls. LL-37 was positively correlated with age. HNP 1-3 levels were increased in groups with DM when compared to the groups without periodontitis. The role of AMPs is vital in the immunoinflammatory response in the pathogenesis of periodontitis and DM. PMID: 31522161 [PubMed - in process]
CONCLUSION: Prevalence of severe periodontitis was 10.6%, a lower percentage than other epidemiological studies in Latin America; but still a high proportion of individuals, which would support the importance of preventive and treatment strategies for the country. PMID: 31522152 [PubMed - in process]
CONCLUSIONS: RC individuals in public or academic PMT programs presented with lower periodontal retreatment needs and progression of periodontitis, as well as tooth loss when compared to IC individuals. PMID: 31522149 [PubMed - in process]
Two powerhouses in pharma and medtech are working together to help people with diabetes better manage their condition. Abbott Laboratories and Sanofi will collaborate to integrate glucose sensing and insulin delivery technologies. The two companies will take an innovative approach to connected care by developing tools that combine the Abbott Park, Il-based companyâs FreeStyle Libre technology with Paris-based Sanofiâ²s insulin dosing information. Initially, the collaboration enables data sharing, at the consent of the user, between Abbottâ²s FreeStyle Libre mobile app and...
Journal Name: Journal of Pediatric Endocrinology and Metabolism Issue: Ahead of print
In conclusion, the occurrence of clinically detectable gingival inflammation was lower in heavy smokers than light and moderate smokers. Older age, diabetes, and visible plaque emerged as risk indicators of gingivitis. Plaque and gingival indices are significantly associated regardless of the smoking status.