Hydrogen-Rich Preservation Solution Attenuates Lung Ischemia-Reperfusion Injury after Prolonged Cold Ischemia in a Canine Left Lung Transplant Model

Molecular hydrogen (H2) has been reported as having protective effects on ischemia-reperfusion injury (IRI) in various organs. However, most of the reports are on inhalation of H2. Our group has previously reported the protective effects of H2-rich solution on lung IRI in a rat hilar-clamp model (Takahashi M, et al. Eur J Cardiothorac Surg 2017; 51: 442-448.) and the protective effects of hydrogen-rich preservation solution on lung preservation in a rat left lung transplant (LTx) model (Saito M, et al.

Source: The Journal of Heart and Lung Transplantation - March 16, 2019 Category: Transplant Surgery Authors: H. Kayawake, T.F. Chen-Yoshikawa, M. Saito, S. Hirano, R. Kurokawa, H. Yamagishi, R. Okabe, F. Gochi, J. Tokuno, S. Ueda, Y. Yokoyama, M. Ikeda, H. Oda, Y. Yamada, Y. Yutaka, D. Nakajima, A. Ohsumi, M. Hamaji, H. Date Tags: 9 Source Type: research