Splenectomy reduces infarct volume and neuroinflammation in male but not female mice in experimental stroke
This study provides new information about the sex specific mechanisms of the peripheral immune response in neurodegeneration after stroke and demonstrates the need for representation of both sexes in basic and clinical stroke research.
Source: Journal of Neuroimmunology - Category: Allergy & Immunology Authors: Abby L. Dotson, Jianming Wang, Julie Saugstad, Stephanie J. Murphy, Halina Offner Source Type: research