Polio vaccination coverage and seroprevalence of poliovirus antibodies after the introduction of inactivated poliovirus vaccines for routine immunization in Japan.

Polio vaccination coverage and seroprevalence of poliovirus antibodies after the introduction of inactivated poliovirus vaccines for routine immunization in Japan.
Vaccine. 2019 Feb 28;:
Authors: Satoh H, Tanaka-Taya K, Shimizu H, Goto A, Tanaka S, Nakano T, Hotta C, Okazaki T, Itamochi M, Ito M, Okamoto-Nakagawa R, Yamashita Y, Arai S, Okuno H, Morino S, Oishi K
Abstract
In Japan, the oral poliovirus vaccine (OPV) was changed to 2 types of inactivated poliovirus vaccine (IPV), the standalone conventional IPV (cIPV) and the Sabin-derived IPV combined with diphtheria-tetanus-acellular pertussis vaccine (DTaP-sIPV), for routine immunization in 2012. We evaluated polio vaccination coverage and the seroprevalence of poliovirus antibodies using data from the National Epidemiological Surveillance of Vaccine-Preventable Diseases (NESVPD) from 2011 to 2015. Several years before the introduction of IPV in 2012, OPV administration for children was refused by some parents because of concerns about the risk of vaccine-associated paralytic poliomyelitis. Consequently, in children aged <1 years who were surveyed in 2011-2012, polio vaccination coverage (45.0-48.8%) and seropositivity rates for poliovirus (type 1: 51.7-65.9%, type 2: 48.3-53.7%, and type 3: 15.0-29.3%) were decreased compared to those surveyed in 2009. However, after IPV introduction, the vaccination coverage (95.5-100%) and seropositivity rates (type 1: 93.2-96.6%, type 2: 93...

Source: Vaccine - February 27, 2019 Category: Allergy & Immunology Authors: Satoh H, Tanaka-Taya K, Shimizu H, Goto A, Tanaka S, Nakano T, Hotta C, Okazaki T, Itamochi M, Ito M, Okamoto-Nakagawa R, Yamashita Y, Arai S, Okuno H, Morino S, Oishi K Tags: Vaccine Source Type: research