Can Presurgical Ultrasound Predict Survival in Women With Ovarian Masses?

This study aimed to determine the ability of ultrasound to predict survival and detect more aggressive tumors in women with ovarian masses. Materials and methods Institutional review board approval was obtained. A total of 167 patients who presented with adnexal mass/masses were included. These were documented as benign or malignant on ultrasound. Age, date of diagnosis and date of death, type of tumor, and tumor marker cancer antigen 125 (CA-125) values were recorded. A CA-125 value of less than 35 U/mL was considered normal. All cases underwent surgery. Pathologic findings were considered as reference standard. The 2 × 2 cross-tabulations were used to correlate dichotomized CA-125, US diagnosis (benign vs malignant), and pathologic status. Difference of distributions was tested using the Wilcoxon rank sum test, and their association was tested using the Fisher exact test. All tests were 2-sided, and P values of 0.05 or less were considered statistically significant. Kaplan-Meir curves were generated to estimate survival. Results There was a statistically significant difference in patients with benign versus malignant tumors based on pathology (P
Source: Ultrasound Quarterly - Category: Radiology Tags: Original Research Source Type: research