Changes in Patient-Reported Outcomes Between Continuers and Discontinuers of Disease Modifying Therapy in Patients with Multiple Sclerosis over age 60

ConclusionMost patients over age 60 who discontinued DMT remained off treatment. Among the outcomes, only EQ-5D demonstrated significant differences over time, with continuers having lower quality of life scores compared to DBD. There were no significant group differences in PS, T25FW and PHQ-9. Overall, stopping DMT appears to have minimal effect on outcomes over the study period in patients over age 60.
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research