Impact of germinal center-associated nuclear protein polymorphisms on breast cancer risk and prognosis in a Japanese population.

CONCLUSIONS: The G allele of rs2839178 at the GANP locus was significantly associated with reduced breast cancer risk and longer DFS in breast cancer patients, showing a consistent direction in the association between susceptibility and clinical outcome. GANP is, therefore, important for the occurrence and progression of sporadic breast cancer.
PMID: 30810967 [PubMed - as supplied by publisher]

Source: Breast Cancer - February 27, 2019 Category: Cancer & Oncology Authors: Kotani H, Ito H, Kuwahara K, Kuzushima K, Iwata H, Tsunoda N, Nagino M, Matsuo K Tags: Breast Cancer Source Type: research