Macrophage migration inhibitory factor plays an essential role in ischemic preconditioning mediated cardioprotection

In conclusion, MIF plays a critical role in IPC-mediated cardioprotection under ischemic stress by activating RISK signalling pathway and AMPK. These results provide an insight for developing a novel therapeutic strategy that target MIF to protect ischemic hearts.

Source: Clinical Science - February 25, 2019 Category: Biomedical Science Authors: Ruze, A., Chen, B.-D., Liu, F., Chen, X.-C., Gai, M.-T., Li, X.-M., Ma, Y.-T., Du, X.-J., Yang, Y.-N., Gao, X.-M. Tags: PublishAheadOfPrint Source Type: research