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U.N. Concerned Over Ebola Backlash

Anthony Banbury, Special Representative of the Secretary-General and Head of the UN Mission for Ebola Emergency Response (UNMEER), visits a safe burial site for Ebola victims in Freetown, Sierra Leone. Credit: UN Photo/Ari GaitanisBy Thalif DeenUNITED NATIONS, Nov 17 2014 (IPS)The United Nations, which is working on an emergency footing to battle the outbreak of Ebola, is worried about the potential for further isolation of the hardest-hit nations in West Africa.“It’s a psychological fear,” Secretary-General Ban Ki-moon told IPS. “And there has been a chain reaction.”He cautioned there should be no action which is not based on science or medical evidence.Ban said the fight against Ebola is a “top priority” of the United Nations and admitted he was conscious of the fact the disease has had a “heavy impact on all spectrum of our lives.”The secretary-general’s warning resonated in North Africa last week when Morocco postponed hosting the 2015 Africa Cup of Nations because of its own fears over the possible spread of the Ebola virus.Morocco’s Sports Minister Mohamed Ouzzine was quoted as saying: “This decision is motivated mainly by the medical risks that this virus would put on the health of our fellow Africans.”The New York Times said “fear of the spread of Ebola has now thrown Africa’s most important soccer tournament into disarray.”As a result, the Confederation of African Football...
Source: IPS Inter Press Service - Health - Category: Global & Universal Authors: Tags: Africa Development & Aid Featured Food & Agriculture Global Headlines Health Humanitarian Emergencies IPS UN: Inside the Glasshouse Population Poverty & MDGs TerraViva United Nations Africa Cup of Nations ebola Guinea Liberia Source Type: news

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Tramontano The interferon (IFN) system is the first line of defense against viral infections. Evasion of IFN signaling by Ebola viral protein 24 (VP24) is a critical event in the pathogenesis of the infection and, hence, VP24 is a potential target for drug development. Since no drugs target VP24, the identification of molecules able to inhibit VP24, restoring and possibly enhancing the IFN response, is a goal of concern. Accordingly, we developed a dual signal firefly and Renilla luciferase cell-based drug screening assay able to quantify IFN-mediated induction of Interferon Stimulated Genes (ISGs) and its inhibition ...
Source: Viruses - Category: Virology Authors: Tags: Article Source Type: research
(Texas Biomedical Research Institute) During the West African Ebola outbreak that began in 2013, an experimental biopharmaceutical drug called ZMappTM was a glimmer of hope in the midst of a health crisis. Now, scientists at Texas Biomedical Research Institute in San Antonio have been awarded a $2 million dollar contract by the makers of ZMapp, Mapp Biopharmaceutical, Inc., to further test this promising new therapeutic.
Source: EurekAlert! - Biology - Category: Biology Source Type: news
[VOA] More than 100,000 malaria cases went untreated when Liberia's health care system buckled under the 2014-2015 Ebola outbreak, according to a new study.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
(PLOS) The Ebola virus disease (EVD) outbreak in 2014-2015 disrupted the provision of healthcare in Sierra Leone, Guinea, and Liberia. In a research article published this week in PLOS Medicine, Bradley Wagenaar, of the University of Washington, and colleagues quantify the health system output losses in Liberia during and in the immediate aftermath of the EVD outbreak, and the recovery of the health systems in the two years following.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news
by Bradley H. Wagenaar, Orvalho Augusto, Jason Beste, Stephen J. Toomay, Eugene Wickett, Nelson Dunbar, Luke Bawo, Chea Sanford Wesseh BackgroundThe aim of this study is to estimate the immediate and lasting effects of the 2014 –2015 Ebola virus disease (EVD) outbreak on public-sector primary healthcare delivery in Liberia using 7 years of comprehensive routine health information system data. Methods and findingsWe analyzed 10 key primary healthcare indicators before, during, and after the EVD outbreak using 31,836 facility-month service outputs from 1 January 2010 to 31 December 2016 across a census of 379 public-se...
Source: PLoS Medicine - Category: Internal Medicine Authors: Source Type: research
Publication date: February 2018 Source:Current Opinion in Virology, Volume 28 Author(s): Anita K McElroy, Elke Mühlberger, César Muñoz-Fontela Since its initial emergence in 1976 in northern Democratic Republic of Congo (DRC), Ebola virus (EBOV) has been a global health concern due to its virulence in humans, the mystery surrounding the identity of its host reservoir and the unpredictable nature of Ebola virus disease (EVD) outbreaks. Early after the first clinical descriptions of a disease resembling a ‘septic-shock-like syndrome’, with coagulation abnormalities and multi-system organ failu...
Source: Current Opinion in Virology - Category: Virology Source Type: research
CONCLUSION: Overall, the findings suggest that it is possible to train staff from ETCs to deliver effective CBT interventions to peers. The implications of these results are discussed, including suggestions for future research and clinical intervention implementation within this population. The limitations of this research are also addressed. PMID: 29432085 [PubMed - in process]
Source: The International Journal of Social Psychiatry - Category: Psychiatry Authors: Tags: Int J Soc Psychiatry Source Type: research
ConclusionWe conclude that there is a place for OSINT and SIGINT in the detection and reporting of outbreaks. However, such tools are not sufficient on their own and must be corroborated for the intelligence to be relevant and actionable. Finally, we conclude that further discussion on key ethical issues needs to take place before such research can continue. In particular, this involves questions of jurisdiction, data ownership, and ethical considerations.
Source: Journal of Public Health - Category: Health Management Source Type: research
Publication date: March 2018 Source:Antiviral Research, Volume 151 Author(s): Wenjun Zhu, Zirui Zhang, Shihua He, Gary Wong, Logan Banadyga, Xiangguo Qiu Filoviruses, such as Marburg and Ebola viruses, cause severe disease in humans with high case fatality rates and are therefore considered biological threat agents. To date, no licensed vaccine or therapeutic exists for their treatment. T-705 (favipiravir) is a pyrazinecarboxamide derivative that has shown broad antiviral activity against a number of viruses and is clinically licenced in Japan to treat influenza. Here we report the efficacy of T-705 against Marburg virus ...
Source: Antiviral Therapy - Category: Virology Source Type: research
PAE said Friday it has acquired Silver Spring-based Macfadden&Associates, which does disaster response work for the U.S. Agency for International Development (USAID). The deal will expand the Arlington government services contractor’s customer reach and build on support work it did for USAID in response to the 2014 Ebola outbreak. Macfadden’s capabilities also mesh well with PAE contracts at the Department of State, CEO John Heller said.  Terms of the dea l weren’t disclosed.  Macfadden…
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
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