Neither fluid rate nor sodium content affect neurocognitive outcomes in DKA

Kuppermann N, Ghetti S, Schunk JE, Stoner MJ, Rewers A, McManemy JK. Clinical Trial of Fluid Infusion Rates for Pediatric Diabetic Ketoacidosis. N Engl J Med 2018;378:2275-87.
Source: The Journal of Pediatrics - Category: Pediatrics Authors: Tags: Current Best Evidence Source Type: research

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CONCLUSION: High Galectin-3, MMP-9, and ST-2 are independently influenced to a certain degree by demographic, clinical and laboratory characteristics. However, no single characteristic was found to be commonly associated with all of the three biomarkers. PMID: 31438834 [PubMed - as supplied by publisher]
Source: Cardiovascular and Hematological Disorders Drug Targets - Category: Drugs & Pharmacology Tags: Cardiovasc Hematol Disord Drug Targets Source Type: research
TYPE 2 diabetes is a life-long condition that requires a person to overhaul aspects of their lifestyle to avert the risks. Mike Trenell, founder and CEO of changing Health sheds a light on a vital yet too often overlooked area of diabetes management - behavioural science.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Publication date: Available online 23 August 2019Source: American Journal of Kidney DiseasesAuthor(s): Enrico Fiaccadori, Carmela Cosola, Alice Sabatino
Source: American Journal of Kidney Diseases - Category: Urology & Nephrology Source Type: research
ConclusionOnly a few cases of penile FG have been reported. Early debridement of all necrotic tissue is the golden rule.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
Authors: Al Shidhani KSH, Al Maani AS, Al Jabri ATJ Abstract Subcutaneous fat necrosis of newborn is a form of panniculitis that often occurs in term and post-term neonate with predisposing risk factors such as perinatal asphyxia and maternal gestational diabetes. A cutaneous involvement may be associated with metabolic complications such as hypoglycemia, hypercalcemia and hypertriglyceridemia. Here, we present a case of Subcutaneous fat necrosis of newborn with bilateral symmetrical involvement of both axillas in a perinatal asphyxiated newborn that has not been previously described in the literature. In this case...
Source: Oman Medical Journal - Category: Middle East Health Tags: Oman Med J Source Type: research
Purpose: Among eyes with proliferative diabetic retinopathy, identify whether baseline characteristics impact the benefit of ranibizumab over panretinal photocoagulation (PRP) in DRCR.net Protocol S. Methods: Participants had proliferative diabetic retinopathy, visual acuity of 20/320 or better, and no previous PRP. Eyes were randomized to PRP or intravitreous 0.5-mg ranibizumab. Results: Ranibizumab was superior to PRP for change in visual acuity and development of vision-impairing central-involved diabetic macular edema over 2 years (P
Source: RETINA - Category: Opthalmology Tags: Original Study Source Type: research
Conclusion: Multispectral imaging displayed an excellent agreement with fundus fluorescein angiography in DR grading, which suggested that it might serve as a new diagnostic technique and an informative tool for evaluating DR.
Source: RETINA - Category: Opthalmology Tags: Original Study Source Type: research
Purpose: To quantify retinal microvascular alterations using optical coherence tomography angiography in diabetic patients, and to evaluate the accuracy of decreased vessel density (VD) in predicting early diabetic retinopathy (DR). Methods: One hundred and two eyes of 51 diabetic patients and 92 eyes of 46 individuals without diabetes were examined. Duration of diabetes, insulin therapy, blood pressure, HbA1C, dyslipidemia, axial length, and the presence of DR were recorded. Retinal VD was measured using optical coherence tomography angiography. The effect of risk factors on VD and on DR was assessed using multivaria...
Source: RETINA - Category: Opthalmology Tags: Original Study Source Type: research
Purpose: To evaluate the clinical effectiveness of intravitreal bevacizumab (IVB) injection combined with cataract surgery in the treatment of patients with cataract and coexisting diabetic retinopathy (DR). Methods: Pertinent comparative studies were identified through systemic searches of PubMed, EMBASE, and the Cochrane Controlled Trials Register up to March 1, 2016. Outcome measures included corrected distance vision acuity, central macular thickness, and progression of DR and maculopathy. A meta-analysis was performed using RevMan (Cochrane Collaboration, Oxford, United Kingdom). Results: Six studies describin...
Source: RETINA - Category: Opthalmology Tags: Original Study Source Type: research
ConclusionsMetS-Z remained linked to future CHD and diabetes when assessed from non-fasting samples. A score such as this may allow for identification of at-risk individuals and serve as a motivation toward interventions to reduce risk.
Source: Nutrition, Metabolism and Cardiovascular Diseases - Category: Nutrition Source Type: research
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