Relationship between tumor-associated immune infiltrate and p16 staining over clinicopathological features in acral lentiginous melanoma.

CONCLUSIONS: Higher levels of TIL tend to be associated with better overall survival in ALM. Loss of expression of p16 is associated with lower levels of CD3+ and CD8+ TIL, indicating a probable relationship between p16 and TIL immune response in ALM . PMID: 30778854 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30778854?dopt=Abstract

Source: Clinical Breast Cancer - February 16, 2019 Category: Cancer & Oncology Authors: Castaneda CA, Castillo M, Torres-Cabala C, Bernabe LA, Casavilca S, Villegas V, Sanchez J, de la Cruz M, Dunstan J, Cotrina JM, Gomez HL, Chavez C, Landa-Baella MP, Tello K, Felix BF, Abugattas J Tags: Clin Transl Oncol Source Type: research