Translating transcription: proteomics in chronic rhinosinusitis with nasal polyps reveals significant discordance with messenger RNA expression

ConclusionProteomic analysis in CRSwNP has revealed novel disease ‐associated proteins and pathways, yet correlates poorly with transcriptomic data. The increasing availability of proteomic arrays opens the door to new potential explanatory mechanisms in CRSwNP and suggests that mRNA based studies should be validated with protein analysis.

Source: International Forum of Allergy and Rhinology - February 18, 2019 Category: Allergy & Immunology Authors: Alan D. Workman, Angela L. Nocera, Sarina K. Mueller, Hasan H. Otu, Towia A. Libermann, Benjamin S. Bleier Tags: ORIGINAL ARTICLE Source Type: research