First bloodstream infection due to Prototheca zopfii var. hydrocarbonea in an immunocompromised patient

Publication date: Available online 16 February 2019Source: Medical Mycology Case ReportsAuthor(s): Norma Beatriz Fernández, Constanza Giselle Taverna, Matías Vivot, Susana Córdoba, Lucia ParavanoAbstractHere we describe a bloodstream infection due to P. zopfii var. hydrocarbonea in a patient with acute lymphoblastic leukemia. Identification was performed by DNA sequencing of the D1/D2 domain of 26s ribosomal DNA and by MALDI-TOF MS technique. Antifungal susceptibility tests against amphotericin B, fluconazole, itraconazole, and voriconazole showed the following MIC values, respectively: 0.25 mg/L, 128 mg/L, 0.064 mg/L, and 0.125 mg/L. The patient received amphotericin B treatment with a successful outcome.
Source: Medical Mycology Case Reports - Category: Biology Source Type: research