Intra-cavitary pulmonary cryptococcoma in poorly controlled diabetes mellitus
Publication date: Available online 24 February 2020Source: Medical Mycology Case ReportsAuthor(s): Najibu Kalyango, Richard Kwizera, Joseph B. Baluku, Felix Bongomin (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - February 26, 2020 Category: Biology Source Type: research

Pleural aspergillosis in a patient with recurrent spontaneous pneumothorax: the challenge of an optimal therapeutic approach
We report a case of PA in a young patient after pleurodesis for recurrent pneumothorax. Clinical resolution was achieved with systemic and local antifungal therapy combined with surgical debridement. Hepatotoxicity led to a switch from voriconazole to isavuconazole, with a successful outcome. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - February 24, 2020 Category: Biology Source Type: research

The Robust and Rapid Role of Molecular Testing in Precision Fungal Diagnostics: A Case Report
Publication date: Available online 13 February 2020Source: Medical Mycology Case ReportsAuthor(s): Julie M. Steinbrink, David K. Hong, Stephen P. Bergin, Rami N. Al-Rohil, John R. Perfect, Eileen K. MaziarzABSTRACTDiagnosis of invasive fungal disease remains an ongoing challenge for clinicians, while continuously evolving treatment regimens increase patient risk for invasive infection. This case highlights how molecular testing led to the diagnosis of co-infection with two fungal pathogens producing invasive disease in a hematopoietic stem cell transplant recipient with graft-versus-host disease (GVHD). (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - February 13, 2020 Category: Biology Source Type: research

Unusual case of otomycosis caused by Saksenaea vasiformis
We report an unusual case of S. vasiformis otitis occurring in a diabetic woman after penetration of an insect in the right ear. Direct microscopic examination of the clinical sample showed hyaline and non septate hyphae belonging to the order Mucorales. Fungal identification was performed by sequencing the ITS region of the rDNA. To our knowledge, this is the first report of S. vasiformis infection in Tunisia. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - February 8, 2020 Category: Biology Source Type: research

Onychomycosis caused by Pichia guilliermondii: a case report and mini-review
Publication date: Available online 8 February 2020Source: Medical Mycology Case ReportsAuthor(s): Mei-jie Zhang, Guan-zhao Liang, Huan Mei, Ge Song, Wei-da LiuAbstractOnychomycosis has been reported to be mainly caused by dermatophytes. Recently, more attention has been paid to yeast for its increasing morbidity, especially the candida specices. Here we reported a fingernail infection caused by Pichia guilliermondii, the sexual reproduction period of Candida guilliermondii. Itraconazole was used for three courses, and the patient achieved improvement without any significant side-effects. This might be the first onychomycos...
Source: Medical Mycology Case Reports - February 8, 2020 Category: Biology Source Type: research

Granulomatous mastitis due to coinfection with Histoplasma sp. and Paracoccidioides sp.: A case report
Publication date: March 2020Source: Medical Mycology Case Reports, Volume 27Author(s): Rommie Merino-Alado, Jacinto Pineda, Juan Hernandez Rasquin, Maria Eugenia Landaeta, Sofía Mata-EssayagAbstractA 51 years old female patient with granulomatous mastitis diagnosis, was referred to the Medical Mycology Department “Dr. Dante Borelli” at the Instituto de Medicina Tropical, Universidad Central de Venezuela (IMT-UCV). Mycological diagnosis demonstrated the presence of intracellular yeast structures suggesting Histoplasma sp. and also multi-budding structures compatible with Paracoccidioides sp. To the best o...
Source: Medical Mycology Case Reports - January 23, 2020 Category: Biology Source Type: research

Microsporidial stromal keratitis in a cat
Publication date: Available online 16 January 2020Source: Medical Mycology Case ReportsAuthor(s): Kelly A. Caruso, Seth Koch, Benjamin D. Reynolds, Kathy Szabo, Mark Mense, Ann Cali, Cameron J. Whittaker, Jeffrey SmithABSTRACTA 12 year-old female spayed felid presented after a 35 day history of right eye pain. On examination, a sub-epithelial opacity was identified in the cornea. A lamellar keratectomy was performed and histopathological analysis revealed low numbers of 2x4um, Gram, Hamatoxylin-eosin and Gomori methanamine-silver positive spores. Transmission electron microscopy found ultrastructural findings consistent wi...
Source: Medical Mycology Case Reports - January 17, 2020 Category: Biology Source Type: research

Neurological worsening during treatment of an immunocompetent adult with Cryptococcus neoformans meningitis
We describe here a young immuncompetent adult of Indian origin from Ghana, West Africa with cryptococcal meningitis who had several ups and downs during his treatment. First he developed neurologic worsening due to premature transition from intensive to consolidation phase therapy. Subsequently he deteriorated due to “immune reconstitution inflammatory syndrome (IRIS)” like phenomenon that necessitated the prolonged use of steroids. Additionally he suffered serious adverse effects due to antifungal drugs including liposomal amphotericin B and flucytosine. He recovered after 16 months of treatment. The case high...
Source: Medical Mycology Case Reports - January 17, 2020 Category: Biology Source Type: research

Sporotrichosis: the case series in Thailand and literature review in Southeast Asia
Publication date: Available online 16 January 2020Source: Medical Mycology Case ReportsAuthor(s): Dissaruj Tovikkai, Warittha Maitrisathit, Chutika Srisuttiyakorn, Jakapat Vanichanan, Arsa Thammahong, Chusana SuankratayABSTRACTHuman Sporotrichosis is an infection caused by dimorphic fungus, Sporothrix schenckii complex, via direct inoculation. We are herein report proven 2 cases of sporotrichosis along with a literature review about human sporotrichosis in the southeast Asian region. The first case was a 76-year-old female with a non-progressive erythematous plaque at the right ankle. The second case was a 36-year-old fema...
Source: Medical Mycology Case Reports - January 17, 2020 Category: Biology Source Type: research

Biological properties of Phoma macrostoma related to non-dermatophyte onychomycosis
We report a rare case of non-dermatophytic onychomycosis of the toenail caused by Phoma macrostoma. Was studied the biological properties of the strain isolated in Kazakhstan. P. macrostoma forms pink colonies, the reverzum is pink-orange. The mycelium is colorless, septate. The appearance of growth tubes from pycnidospores occurs within 12 hours, mycelial growth and branching after 18 hours, the appearance of pycnids is 48 hours. The saccharolytic and urease activity of the strain is low. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - January 17, 2020 Category: Biology Source Type: research

Successful treatment of rhino-facial mucormycosis in a diabetic patient
We report a case of rhinofacial mucormycosis in a 39-year-old diabetic patient. The diagnosis was established by clinical examination, imaging, and confirmed by mycological examination. Rhizopus arrhizus was isolated. He was successfully treated with amphotericin B, surgical resection, diabetes control and hyperbaric oxygen therapy. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - January 17, 2020 Category: Biology Source Type: research

GRANULOMATUSE MASTITIS DUE TO COINFECTION WITH Histoplasma sp. and Paracoccidioides sp.: A CASE REPORT
Publication date: Available online 16 January 2020Source: Medical Mycology Case ReportsAuthor(s): Rommie Merino-Alado, Jacinto Pineda, Juan Hernandez Rasquin, Maria Eugenia Landaeta, Sofía Mata-EssayagABSTRACTA 51 years old female patient with granulomatous mastitis diagnosis, was referred to the Medical Mycology Department “Dr. Dante Borelli” at the Instituto de Medicina Tropical, Universidad Central de Venezuela (IMT-UCV). Mycological diagnosis demonstrated the presence of intracellular yeast structures suggesting Histoplasma sp. and also multi-budding structures compatible with Paracoccidioides sp. To...
Source: Medical Mycology Case Reports - January 17, 2020 Category: Biology Source Type: research

Cutaneous phaeohyphomycosis caused by Exophiala xenobiotica: A case report
We report a case of phaeohyphomycosis that affected the leg of a 45-year-old Brazilian man, car mechanic and renal transplanted. The direct mycological examination evidenced dematiaceous septated hyphae. The pathogenic fungal species was identified as Exophiala xenobiotica. Antifungal activity in vitro revealed terbinafine as the best antifungal. For treatment, it was chosen surgical excision of the entire lesion and used systemic itraconazole. Phaeohyphomycosis caused by Exophiala xenobiotica is extremely rare and is closely related to transplant patients. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - December 27, 2019 Category: Biology Source Type: research

Feline disseminated cutaneous phaeohyphomycosis due to Exophiala spinifera
Publication date: Available online 24 December 2019Source: Medical Mycology Case ReportsAuthor(s): Julie-Anne Daly, Vit Hubka, Alena Kubátová, Marina Gimeno, Vanessa BarrsAbstractA six-year-old domestic shorthair cat was presented for a subcutaneous digital nodular lesion on the right forelimb. On physical examination a similar lesion was identified on the right hindlimb. Disseminated cutaneous phaeohyphomycosis was diagnosed from histopathological changes in representative tissue biopsies and fungal culture. The isolate was identified by sequencing of ITS rDNA as Exophiala spinifera. This is the first report...
Source: Medical Mycology Case Reports - December 24, 2019 Category: Biology Source Type: research

HIV-associated disseminated histoplasmosis successfully treated with isavuconazole consolidation therapy
Publication date: Available online 20 December 2019Source: Medical Mycology Case ReportsAuthor(s): Andrea Mazzella, Neil RH. Stone, Erica RM. Pool, Ana García Mingo, Sorina Bolache, Chris WoodAbstractA 30-year-old man with advanced HIV and disseminated histoplasmosis deteriorated after stepping down from intravenous liposomal amphotericin B to itraconazole.Therapeutic levels of itraconazole and posaconazole were not achieved, therefore liposomal amphotericin B was reintroduced. Stepdown treatment was switched to oral isavuconazole; since then the patient has remained well. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - December 21, 2019 Category: Biology Source Type: research

Achievement of long-term remission of disseminated histoplasmosis in an AIDS patient
Publication date: Available online 19 December 2019Source: Medical Mycology Case ReportsAuthor(s): Akihide Nakamura, Isao Tawara, Kazuko Ino, Takeshi Matsumoto, Akinobu Hayashi, Hiroshi Imai, Yasunori Muraosa, Katsuhiko Kamei, Naoyuki KatayamaAbstractHistoplasmosis, a fungal infection caused by Histoplasma capsulatum, is poor prognosis once it disseminated, especially in immunocompromised patients. A 50-year-old Japanese-Brazilian male with multiple cervical lymphadenopathies was diagnosed as disseminated histoplasmosis and acquired immunodeficiency syndrome (AIDS). Anti-fungal therapy was initiated followed by anti-retrov...
Source: Medical Mycology Case Reports - December 20, 2019 Category: Biology Source Type: research

Influenza-associated pulmonary aspergillosis in a patient on ECMO
In this report, we would like to present a case of pulmonary aspergillosis following influenza infection for the first time in Kuwait, and raise awareness about such unrecognized threatening co-infection. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - December 20, 2019 Category: Biology Source Type: research

Fatal chronic meningitis caused by Candida dubliniensis after liver transplantation
We report a case of fatal chronic Candida dubliniensis meningitis complicated by severe hydrocephalus secondary to liver transplantation, in which diagnosis was considerably delayed. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - December 18, 2019 Category: Biology Source Type: research

Persistent candida arthritis successfully treated with micafungin instillation and surgery. A case report
We report a rare case of C. krusei knee arthritis treated with instillation of micafungin and arthroscopy. A 49-year-old man hospitalized for treatment of Acute Myeloid Leukemia developed knee arthritis with C. krusei. He was treated with a combination of arthroscopic debridement, intravenous as well as intra-articular micafungin. Serum and intra-articular concentrations of micafungin were determined. After instillation of micafungin in the knee and arthroscopic debridement, the patient completely recovered. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - December 18, 2019 Category: Biology Source Type: research

Complication of massive trauma by fungal infection and bone tuberculosis
We report a middle aged man who was admitted with severe necrotising fasciitis following a motor vehicle accident (MVA). Histopathology of the excised tissue suggested mucormycosis while a bone tissue culture revealed fully sensitive Mycobacterium tuberculosis. He received intravenous liposomal amphotericin B combined with multiple surgical debridements and ended with right shoulder disarticulation. In addition he completed a nine months course of anti-tuberculosis treatment. He remained stable one year following his admission.We believe that trauma contributed to both conditions by direct inoculation of fungal spores and ...
Source: Medical Mycology Case Reports - December 10, 2019 Category: Biology Source Type: research

A case of CNS aspergillosis in a patient with chronic lymphocytic leukemia on first-line ibrutinib therapy
We present a case of CNS aspergillosis in a CLL patient on first line ibrutinib therapy. We summarize existing case reports and case series of invasive aspergillosis in patients on ibrutinib, the pathogenesis of invasive aspergillosis, and discuss the clinical controversies regarding anti-fungal prophylaxis in this population. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - December 6, 2019 Category: Biology Source Type: research

Contact lens associated keratitis due to Tintelnotia destructans
We report the first case of Tintelnotia destructans associated keratitis in a contact lens wearer in Australia. Corneal scrape showed fungal elements on direct microscopy leading to a prompt diagnosis of fungal keratitis and early topical and systemic antifungal therapy. The isolate was eventually identified by ITS gene sequencing. This case highlights the importance of accurate identification and antifungal susceptibility testing for the management of fungal keratitis. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - December 5, 2019 Category: Biology Source Type: research

Cerebral phaeohyphomycosis caused by Alternaria spp.: A case report
This report describes the case of a 66-year-old man with a history of renal transplantation from a cadaveric donor 1 year ago, which was considered as the primary risk factor. The characteristics of the infection, procedures performed, microbiological findings and treatment provided are described. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - December 4, 2019 Category: Biology Source Type: research

Cryptococcus gattii infection in an immunocompetent host in Greece
We report a case of a 31-year-old otherwise healthy female with pulmonary cryptococcoma along with cryptococcal meningitis due to Cryptococcus gattii molecular type VGI, in Greece. Combined antifungal treatment and surgical excision of pulmonary cryptococcoma yielded a good response. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - December 4, 2019 Category: Biology Source Type: research

Multi-fungal sepsis and mucormycosis of the central nervous system in a patient treated with ibrutinib, a case report and review of the literature
We report the case of a 71 years old patient with chronic lymphocytic leukemia (CLL), who developed a rapidly progressing multi-fungal infection including mucormycosis of the central nervous system (CNS) during treatment with ibrutinib.On autopsy mucorales species were demonstrated intravascularly by histomorphology of several organs and lymph nodes and were characterized as Rhizomucor pusillus by polymerase-chain reaction (PCR) – analysis. In addition, invasive pulmonary Aspergillus fumigatus was found and also confirmed by PCR. To the best of our knowledge, this is the first confirmation of a multi-fungal sepsis an...
Source: Medical Mycology Case Reports - December 3, 2019 Category: Biology Source Type: research

False-negative result of serum cryptococcal antigen lateral flow assay in an HIV-infected patient with culture-proven cryptococcaemia
We report the case of an HIV-infected patient with CD4 = 42 cells/mL, asthenic, negative serum CrAg lateral flow assay (LFA) and culture-proven cryptococcaemia. Despite the high accuracy of LFA, false-negative is possible and careful clinical evaluation and close follow-up are relevant. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - November 3, 2019 Category: Biology Source Type: research

Invasive dermatophytosis mimicking vasculitis
We report a case of invasive dermatophytosis mimicking vasculitis. A patient consulted the Department of Dermatology, Zealand University Hospital, Roskilde, Denmark for the assessment of violaceous/erythematous lesions thought to be vasculitis. She had prior to this been treated with the immunosuppressive drug teriflunomid. Due to the lesion's erythematous scaling boarder invasive dermatophytosis was suspected. By using direct microscopy a mycological diagnosis was confirmed. We underline the utility of direct microscopy in the diagnosis. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - November 1, 2019 Category: Biology Source Type: research

Meningeal and multiorgan disseminated sporotrichosis: A case report and autopsy study
Publication date: Available online 31 October 2019Source: Medical Mycology Case ReportsAuthor(s): Helena Duani, Marina Fernandes Palmerston, Jésus Faria Rosa Júnior, Vitor Teatini Ribeiro, Pedro Lobo Alcântara NevesAbstractThis case report presents a 36-year old man with a disseminated sporotrichosis who presented with seizures and crusted lesions all over the body. Imaging studies revealed acute ischemic brain event with haemorrhagic transformation in right frontal lobe. Skin biopsy showed Sporothrix schenckii. He was treated with standard amphotericin B. Despite therapy, he developed consciousness los...
Source: Medical Mycology Case Reports - November 1, 2019 Category: Biology Source Type: research

Auxarthron alboluteum related to non-dermatophytic toenail infection in Kurdistan region, Iraq: A case report
We report a rare case of non-dermatophytic onychomycosis of the big toenail caused by Auxarthron alboluteum in a 63-years old Iraqi female with a history of diabetes. The big toenail showed distal subungual onychomycosis with extensive yellow-white discoloration. Identification of the causative agent was confirmed by morphological and microscopical characteristics in culture and analysis of ITS-rDNA region. To the best of our knowledge, the isolated Auxarthron alboluteum reported here is a new etiologic species of nail infection in Iraq and this is the first case of its kind to be reported in the world. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - November 1, 2019 Category: Biology Source Type: research

Presentation of histoplasmosis as mononucleosis syndrome in an immunocompetent patient
We present the case of an 18 year-old immunocompetent, male patient, resident of the State of Florida, who showed signs of mononucleosis syndrome that included odynophagia, cervical adenomegaly, sporadic fever and rash; however, no pulmonary involvement or visceromegaly were present. Faced with this atypical and unexpected clinical picture, histoplasmosis infection was eventually diagnosed following cervical lymph-node biopsy. Disseminated histoplasmosis may have unexpected manifestations, as is pointed out in the case described below. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - October 31, 2019 Category: Biology Source Type: research

An unusual case of cutaneous feline pythiosis
Publication date: Available online 31 October 2019Source: Medical Mycology Case ReportsAuthor(s): Megan Dowst, Alana Pavuk, Raquel Vilela, Camila Vilela, Leonel MendozaAbstractPythiosis is frequently reported in dogs and horses inhabiting tropical, subtropical and temperate areas of the USA, but the disease is rare in domestic cats. The clinical presentation of feline pythiosis includes subcutaneous masses without ulcerated tissue and involvement of the intestinal tract. Here in we report an eight-week-old female unvaccinated stray kitten with an unusual extensive circular ulcerated lesion on her left flank. The lesion did...
Source: Medical Mycology Case Reports - October 31, 2019 Category: Biology Source Type: research

Cutaneous mucormycosis by Rhizopus arrhizus treated with isavuconazole as first line therapy: A case report
We report the case of 67-year-old man with idiopathic granulocytic aplasia and a cutaneous lesion caused by Rhizopus arrhizus treated with isavuconazole. Its safety profile and spectrum of activity make it an important therapeutic option. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - October 4, 2019 Category: Biology Source Type: research

Disseminated gastrointestinal basidiobolomycosis (GIB) in an infant from western India
Publication date: Available online 3 October 2019Source: Medical Mycology Case ReportsAuthor(s): Anuradha Sharma, Rahul Saxena, Arvind Sinha, Shambhavi Singh, Taruna YadavAbstractBasidiobolomycosis is an infection due to the fungus Basidiobolus ranarum, an environmental saprophyte found worldwide. We are reporting youngest case of Gastrointestinal Basidiobolomycosis (GIB) in a two month old boy from India. He presented with a mass in right iliac fossa with the signs of intestinal obstruction. Histopathology of the lesion showed broad aseptate hyphae. It disseminated to kidneys. Aspirate culture from nephrostomy yielded gro...
Source: Medical Mycology Case Reports - October 4, 2019 Category: Biology Source Type: research

First case report of fulminant septic shock from meningococcemia associated with Cryptococcus neoformans coinfection in an immunocompetent patient
We describe a case of an immunocompetent 74-year-old Caucasian woman who presented with fulminant acute meningococcemia associated with cryptococcal meningitis, which progressed to worsening general condition and died of septic shock and multiple organ dysfunctions in less than 48 hours. This case report demonstrates the possibility of coinfections related to Neisseria meningitidis and Cryptococcus neoformans, even in immunocompetent patients, which represent a diagnostic challenge for clinicians, thus encouraging further studies for a better understanding. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - October 4, 2019 Category: Biology Source Type: research

Case report of penile Rhizopus arrhizus infection in an unexpected patient
Publication date: Available online 25 September 2019Source: Medical Mycology Case ReportsAuthor(s): Matthew Bezzant, Kathryn Lago, Tatjana CalvanoAbstractThere are few reports of penile mucormycosis and even fewer in the absence of overt immune suppression. An eighty year old male with diabetes presents with penile mass. The pathology and culture demonstrated Rhizopus arrhizus. He was treated with surgery and liposomal amphotericin B. His therapy was stopped after pathology demonstrated clear surgical margins. His good outcome provides evidence that stopping antifungal therapy after achieving clear surgical margins is acce...
Source: Medical Mycology Case Reports - September 26, 2019 Category: Biology Source Type: research

Fungal aneurism of the right posterior inferior cerebellar artery (PICA)
Publication date: Available online 25 September 2019Source: Medical Mycology Case ReportsAuthor(s): Stefano Tambuzzi, Michele Boracchi, Francesca Maciocco, Cristina Tonello, Guendalina Gentile, Riccardo ZojaAbstractIn this case-report, the Authors show the case of a sudden death occurred in a 38-year-old woman submitted to surgical excision of a right acoustic neurinoma. At the autopsy, was detected a cerebral hemorrhage with multifocal localization by a ruptured rare fungal aneurysm of the Posterior Inferior Cerebellar Arthery (PICA). The PCR analysis, carried out on formalin-fixed paraffin-embedded tissue, identified the...
Source: Medical Mycology Case Reports - September 26, 2019 Category: Biology Source Type: research

Combination of amphotericin B and caspofungin in the treatment of mucormycosis
We report a case of invasive mucormycosis in 52 year-old woman. CT-scan and magnetic resonance imaging found a partial right sinus thrombosis associated with homolateral ethmoidal and maxillary sinusitis with submucosal inflammation. Histopathological examination of excised tissue was positive for mucormycosis. Our patient was treated by surgical debridement and a combination of amphotericin B and caspofungin, with a good outcome. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - September 22, 2019 Category: Biology Source Type: research

Recurrent eumycetoma caused by novel species Madurella pseudomycetomatis: A case report
We present a case of madura foot with novel etiologic agent Madurella pseudomycetomatis. Diagnosis was based on morphologic, physiologic, histipathologic and molecular methods. In vitro antifungal susceptibility tests revealed that MIC values for itraconazole, amphotericin B, and posaconazole were 0.0313 μg/ml, 0.0313μg/ml, and 0.004 μg/ml, respectively. The patient was treated and recovered by itraconazole(400 mg/day) after prolonged course. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - September 22, 2019 Category: Biology Source Type: research

Possible rabbit breeders' Trichophyton mentagrophytes infection characterized by Majocchi's granuloma in immunocompetent host: Case report
We report on a family of three in a rabbit farm, especially children with Majocchi granuloma as the main clinical feature of cross-infection of Trichophyton mentagrophytes, provides experience in reducing the rate of clinical misdiagnosis. Based on the pathological features of Majocchi's granuloma, taking into account that severe inflammatory reactions are also responsible for the damage of the body. In Majocchi's granuloma treatment strategy, we recommend the use of anti-inflammatory Chinese medicines that have a hormonal effect and have no side effects. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - September 22, 2019 Category: Biology Source Type: research

Unusual presentation and urinary tract obstruction due to disseminated intra-abdominal eumycetomas caused by Curvularia species in a dog
Publication date: Available online 19 September 2019Source: Medical Mycology Case ReportsAuthor(s): Joe Herbert, Deborah Chong, Derek Spielman, Mark Krockenberger, Jamie Wildner, Richard BishopAbstractIntra-abdominal eumycetomas are rare in dogs and usually attributed to contamination of surgical wounds post-operatively. This is the first report of extensively disseminated intra-abdominal eumycetomas due to Curvularia resulting in urinary tract obstruction and associated chronic recurrent urinary tract infections in a Labrador retriever. Identification of the fungal genus was performed on samples obtained from culture of e...
Source: Medical Mycology Case Reports - September 21, 2019 Category: Biology Source Type: research

Gastrointestinal Mucormycosis in a two-year-old child: A clinical and radiological enigma
We present a case of GI mucormycosis in a 2-year-old male child who presented with abdominal mass with no underlying risk factors. The aim of this case report is to emphasize on its etiopathogenesis and keeping mucormycosis high in the differential diagnosis in a child presenting with abdominal mass. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - September 21, 2019 Category: Biology Source Type: research

Point mutations in the squalene epoxidase gene of Indian ITS genotype VIII T. mentagrophytes identified after DNA isolation from infected scales
Publication date: Available online 18 September 2019Source: Medical Mycology Case ReportsAuthor(s): Anke Burmester, Uta-Christina Hipler, Reka Hensche, Peter Elsner, Cornelia WiegandAbstractTerbinafine resistant Indian ITS genotype VIII T. mentagrophytes strain was identified by partial sequencing of the squalene epoxidase gene using DNA isolated from infected scales. This method allowed the rapid identification of single point mutations within the squalene epoxidase gene, even before a fungal culture was obtained. Terbinafine resistance was indicated by the amino acid position switch Phe397Leu based on a single point muta...
Source: Medical Mycology Case Reports - September 19, 2019 Category: Biology Source Type: research

First case report of Talaromyces marneffei infection in HIV-infected patient in the city of Ouagadougou (Burkina Faso)
We describe the first case of Talaromycosis in HIV-infected patient in Burkina Faso. This is an 83-year-old man with skin lesions on the right foot. The thick scales were used for the mycological examination. Microscopic examination of growth allowed isolation of Talaromyces marneffei in its yeast and mold forms. The patient was treated successfully with Itraconazole (400 mg/day) for 8 weeks. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - September 19, 2019 Category: Biology Source Type: research

Subcutaneous phaeohyphomycosis from Medicopsis romeroi in a diabetic patient
Publication date: Available online 30 July 2019Source: Medical Mycology Case ReportsAuthor(s): Pattriya Chanyachailert, Charussri Leeyaphan, Sumanas Bunyaratavej, Piriyaporn ChongtrakoolAbstractDematiaceous fungi can cause subcutaneous phaeohyphomycosis, an uncommon fungal infection of the dermis and subcutaneous tissues. Medicopsis romeroi is an emerging organism that can infect patients with subcutaneous phaeohyphomycosis, especially immunocompromised patients. The present case involved subcutaneous phaeohyphomycosis caused by Medicopsis romeroi in an 80-year-old Thai male with poorly controlled diabetes, for whom the le...
Source: Medical Mycology Case Reports - August 23, 2019 Category: Biology Source Type: research

Cerebral aspergillosis presenting as a space occupying lesion in an immunocompetent individual
Publication date: Available online 1 August 2019Source: Medical Mycology Case ReportsAuthor(s): Georges El Hasbani, Joseph Chirayil, Sutasinee Nithisoontorn, Arturo Alvarez Antezana, Ibrahim El Husseini, Maria Landaeta, Yasir Saeed, Richard AssakerAbstractCerebral aspergillosis has the tendency to occur in immunocompromised patients. Less commonly, immunocompetent individuals can be affected, with neuroimaging findings being difficult to interpret. The diagnosis necessitates imaging of the brain as well as the sinuses with biopsy and pathological confirmation. A surgical excision with aggressive antifungal agents are requi...
Source: Medical Mycology Case Reports - August 3, 2019 Category: Biology Source Type: research

Gastrointestinal ucormycosis in a two-year-old child: A clinical and radiological enigma
We present a case of GI mucormycosis in a 2-year-old male child who presented with abdominal mass with no underlying risk factors. The aim of this case report is to emphasize on its etiopathogenesis and keeping mucormycosis high in the differential diagnosis in a child presenting with abdominal mass. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - August 3, 2019 Category: Biology Source Type: research

Disseminated histoplasmosis in immunocompetent patients from an arid zone in Western India: A case series
We report two cases of disseminated histoplasmosis in immunocompetent individuals from a non-endemic zone in Western India. Rapid diagnostic tests like urinary antigen detection and molecular assays comprise the need of the hour as early initiation of antifungal therapy can be life-saving. Clinicians need to be aware of this entity to prevent misdiagnosis and initiate prompt effective management. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - August 1, 2019 Category: Biology Source Type: research

A rare case of Myrothecium species causing mycotic keratitis: Diagnosis and management
We report two cases of keratitis caused by a rare fungus Myrothecium species. Clinical presentation, identification, and management were studied. Both fungi were grown from corneal scraping and identified as M. verrucaria and M. gramineum based on the microbiological techniques and DNA sequencing analysis. Both patients were treated with topical natamycin and or voriconazole/econazole. In the first patient, there was total healing of the with scar formation, however, the prognosis was poor in the second patient. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 31, 2019 Category: Biology Source Type: research

Peritoneal dialysis (PD) catheter-related peritonitis from Aureobasidium pullulans caused by poor caregiver's hand hygiene
We report the first case of PD patients with catheter-related peritonitis form Aureobasidium pullulans, a black yeast-like dematiaceous fungus, and reviewing the relevant literatures. A potential cause of this infection is poor hand hygiene and improper fingernail care. The infection could be prevented if patient and caregiver strictly follow hand-washing protocols. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 31, 2019 Category: Biology Source Type: research

Subcutaneous phaeohyphomycosis from Medicopsis romeroi in a diabetic patient: A case report
Publication date: Available online 30 July 2019Source: Medical Mycology Case ReportsAuthor(s): Pattriya Chanyachailert, Charussri Leeyaphan, Summanas Bunyaratavej, Piriyaporn ChongtrakoolAbstractDematiaceous fungi can cause subcutaneous phaeohyphomycosis, an uncommon fungal infection of the dermis and subcutaneous tissues. Medicopsis romeroi is an emerging organism that can infect patients with subcutaneous phaeohyphomycosis, especially immunocompromised patients. The present case involved subcutaneous phaeohyphomycosis caused by Medicopsis romeroi in an 80-year-old Thai male with poorly-controlled diabetes, for whom the l...
Source: Medical Mycology Case Reports - July 31, 2019 Category: Biology Source Type: research