Trichophyton benhamiae and T. mentagrophytes target guinea pigs in a mixed small animal stock
We present a case of a small animal stock infected with two Trichophyton species. T. benhamiae was isolated from 15 out of 26 (58%) guinea pigs including two morphologically different phenotypes. Eight guinea pigs were infected with T. benhamiae and T. mentagrophytes simultaneously. The animals showed alopecia and crusts or no clinical signs at all. T. benhamiae was not detected in rats, rabbits and mice kept in the same stock. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - December 1, 2018 Category: Biology Source Type: research

Breaking the Mold: A case of pulmonary mucormycosis treated with isavuconazole
Publication date: Available online 1 December 2018Source: Medical Mycology Case ReportsAuthor(s): Jonathan Huggins, Ayman Al Jurdi, Renuka GuptaAbstractPulmonary mucormycosis is a rare opportunistic invasive fungal infection that disproportionately affects immunocompromised hosts and carries high morbidity and mortality. It is traditionally treated with combined pharmacologic and surgical modalities. Here we present a case of pulmonary mucormycosis in a patient whose disease burden precluded surgical management, and in whom acute kidney injury necessitated therapy with an alternative to the recommended pharmacologic antifu...
Source: Medical Mycology Case Reports - December 1, 2018 Category: Biology Source Type: research

Saccharomyces cerevisiae fungemia in a critically ill patient with acute cholangitis and long term probiotic use
We report a case of a 74-year-old man admitted for acute cholangitis taking a probiotic supplement containing the subtype Saccharomyces boulardii. He later developed S. cerevisiae fungemia that was successfully treated with Micafungin and Fluconazole. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - November 14, 2018 Category: Biology Source Type: research

Palate ulcer, uvular destruction and nasal septal perforation caused by Sporothrix brasiliensis in an HIV-infected patient
We report a dramatic presentation of Sporothrix brasiliensis infection, with destruction of the nasal septum, soft palate, and uvula of an HIV-infected woman. She was successfully treated with amphotericin B deoxycholate followed by itraconazole. Sporotrichosis remains a neglected opportunistic infection in patients with AIDS and awareness of this potentially fatal infection is of utmost importance. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - November 14, 2018 Category: Biology Source Type: research

Chronic pulmonary aspergillosis following pulmonary embolism
We describe a case of CPA in a 79-year-old female following bilateral pulmonary emboli. The clinical implications are numerous, including the dilemma of anticoagulation. This link suggests that a lower threshold for suspecting CPA following pulmonary embolus is required, even in the absence of other respiratory disease. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - November 11, 2018 Category: Biology Source Type: research

Treatment of cerebral mucormycosis with drug therapy alone: A case report
We report on an elderly male patient with headache and right-side weakness. Imaging studies revealed multiple space-occupying lesions in the parietal and occipital cerebral regions. Biopsy revealed broad aseptate ribbon-like structures branching at right angles, suggestive of mucormycosis. Improvement was observed after medical therapy with 20 weeks of liposomal amphotericin B (5 mg/kg/day) combined with posaconazole, followed by posaconazole (400 mg twice a day) alone for 1 month. The patient recovered without neurological deficits; however, multidrug-resistant bacteraemia and hospital-acquired pneumonia occurre...
Source: Medical Mycology Case Reports - October 29, 2018 Category: Biology Source Type: research

Deep cutaneous Trichosporon asahii infection in a patient recovering from toxic epidermal necrolysis
We present a case of a patient who developed a deep cutaneous fungal infection caused by Trichosporon asahii and discuss the management. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - October 27, 2018 Category: Biology Source Type: research

Purpuriocillium lilacinum infection in captive loggerhead sea turtle hatchlings
Publication date: Available online 25 October 2018Source: Medical Mycology Case ReportsAuthor(s): Clarisse Máximo Arpini, Yhuri Cardoso Nóbrega, Vinícius Davel Castheloge, Daniel Santos Neves, Carlos Eduardo Tadokoro, Gisela Lara da Costa, Manoel Marques Evangelista Oliveira, Marcelo Renan de Deus SantosAbstractThis paper reports a case of Purpureocillium lilacinum infection in seven loggerhead sea turtle (Caretta caretta) hatchlings kept in an aquarium under inadequate condition. The fungus was isolated from skin and pulmonary lesions. Metilene blue and NaCl solutions, Schinus terebinthifolius and euc...
Source: Medical Mycology Case Reports - October 25, 2018 Category: Biology Source Type: research

Aspergillus Endocarditis Diagnosed by Fungemia Plus Serum Antigen Testing
Publication date: Available online 25 October 2018Source: Medical Mycology Case ReportsAuthor(s): Timothy J. Hatlen, Scott G. Filler, Arnold Bayer, Sonia Shah, Shivani Shodhan, Tam T. VanAbstractFungal endocarditis remains an uncommon clinical diagnosis, though is likely to become more frequent due to the global increase in transplantations and cardiac valvular surgery. A case of prosthetic valve endocarditis due to Aspergillus fumigatus is described that was diagnosed with serologic fungal markers and confirmed with positive blood cultures, an uncommon finding. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - October 25, 2018 Category: Biology Source Type: research

Invasive fungal infection by Aspergillus flavus in immunocompetent hosts: a case series and literature review
Publication date: Available online 25 October 2018Source: Medical Mycology Case ReportsAuthor(s): Ana María Garcia-Giraldo, Barbara Lucia Mora, Jorge Mario Loaiza-Castaño, Jorge Andrés Cedano, Fernando RossoAbstractInvasive aspergillosis usually affects immunocompromised hosts with variable manifestations depending on the site of infection. In this article, we present two cases of invasive Aspergillosis in two non-immunocompromised patients; both cases had a paranasal sinuses infection, with intraorbital and intracranial extension, requiring surgery and antifungal treatment with Voriconazole. These cas...
Source: Medical Mycology Case Reports - October 25, 2018 Category: Biology Source Type: research

Exophiala psychrophila: a new agent of chromoblastomycosis
We report a woman who was treated before with mycological cure, but she experience a relapse requiring treatment again. Direct microscopic examination and skin biopsy with culture were necessary to identify a Exophiala psychrophila, and for our knowledge this is the first case reported. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - October 25, 2018 Category: Biology Source Type: research

Posaconazole and isavuconazole induced hypomagnesaemia
Publication date: Available online 28 September 2018Source: Medical Mycology Case ReportsAuthor(s): John Burston, Mark Robertson, Sebastian van Hal, Angie N. Pinto (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - October 5, 2018 Category: Biology Source Type: research

Aspergillus fumigatus endocarditis in an Indigenous Australian male without classic risk factors
We present the case of an “immunocompetent” Indigenous Australian male with culture confirmed Aspergillus brain abscesses complicating bilateral endocarditis. The reported mortality rate for Aspergillus endocarditis approaches 100%. Despite sub-optimal therapy this patient survived beyond expectation. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - September 22, 2018 Category: Biology Source Type: research

Blastoschizomyces capitatus pneumonia in a patient with untreated chronic lymphocytic leukemia
We report a case of pulmonary infection by B. capitatus in a patient with untreated chronic lymphocytic leukemia. Although the patient had a complete recovery, we believe that this report will alert clinicians to consider B. capitatus as possible cause of severe pneumonia in untreated CLL. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - September 22, 2018 Category: Biology Source Type: research

Invasive rhinocerebral mucormycosis in a patient with liver cirrhosis leading to fatal massive stroke
Publication date: Available online 21 September 2018Source: Medical Mycology Case ReportsAuthor(s): Taher Sabobeh, Kamran Mushtaq, Ahmed Elsotouhy, Adham A. Ammar, Sameera RashidAbstractImmunocompromised status is associated with invasive fungal infections including mucormycosis. These infections are challenging to treat and associated with high overall mortality.Here we report a fatal case of invasive mucormycosis in a cirrhotic, diabetic patient. Despite the swift diagnosis and management; the fungal invasion of the right internal carotid artery lead to massive ischemic stroke.Timely diagnosis and management is crucial f...
Source: Medical Mycology Case Reports - September 22, 2018 Category: Biology Source Type: research

Utilization of Voriconazole Drug Monitoring in the Treatment of Cutaneous Scedosporium apiospermum Infection
We report the use of voriconazole troughs to achieve appropriate therapeutic levels in treatment of a cutaneous Scedosporium apiospermum infection. Following heart transplantation, a 63-year-old immunocompromised patient presented with post-traumatic nodular lesions on his right shin. Pathology showed fungal yeasts with culture revealing Scedosporium apiospermum. According to therapeutic drug monitoring, initial voriconazole treatment was subtherapeutic requiring increased dosing until appropriate therapeutic trough levels were attained, and resolution of the fungal infection was achieved. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - September 14, 2018 Category: Biology Source Type: research

Isolation of Cryptococcus gattii VGIII from feline nasal injury
Publication date: Available online 12 September 2018Source: Medical Mycology Case ReportsAuthor(s): Peggy Vieille, Rodrigo Cruz, Paula León, Nicolás Cáceres, Gustavo GiusianoAbstractHereby we communicate the first autochthon isolation of Cryptococcus gattii VGIII in Chile, which was obtained from a nasal injury in a domestic cat in the Valparaíso region in Chile. The strain was identified using morphophysiological tests, MALDI-TOF, and URA5 gene PCR-RFLP analysis. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - September 13, 2018 Category: Biology Source Type: research

Intracatheter Antifungal Lock Leading to Detrimental Complications
We report two cases where antifungal lock were performed in PD patients presented with PD-related fungal infection that not only had no effect on abating the infection but also causing paradoxical outcomes. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - September 13, 2018 Category: Biology Source Type: research

Post-traumatic fatal disseminated Apophysomyces elegans infection
We describe a case of disseminated post-traumatic Apophysomyces elegans in an immunocompetent patient status-post soil inoculation. Fungi introduced at a deep arm laceration leads to neurovascular invasion and dissemination prior to amputation and systemic treatment. We specify strict post-traumatic wound surveillance protocol and roles of novel tissue tests to improve time to diagnosis and prognosis of frequently fatal post-traumatic Mucorales infections (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - September 7, 2018 Category: Biology Source Type: research

Fatal fulminant cryptococcemia complicating sarcoidosis: is it to be expected?
We describe a case of cryptococcemia that rapidly progressed toward fatality without apparent other sites of infection. We discuss on the importance of serum cryptococcal polysaccharide antigen testing for identifying at-risk patients who might benefit from timely diagnosis and treatment of cryptococcosis (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - August 17, 2018 Category: Biology Source Type: research

Successful treatment of C. auris shunt infection with intraventricular caspofungin
We describe here an adult with nosocomial CSF shunt infection due to multi drug resistant C. auris. Systemic therapy with echinocandin and flucytosine failed. Fortunately, administration of daily intraventricular caspofungin 10 mg for 10 days in conjunction with systemic voriconazole resulted in both clinical and microbiological cure. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - August 12, 2018 Category: Biology Source Type: research

Canine rhinitis caused by an uncommonly-diagnosed fungus, Scedosporium apiospermum
Publication date: Available online 8 August 2018Source: Medical Mycology Case ReportsAuthor(s): Christopher Smith, Lucy Woolford, Jessica Talbot, Ken C Lee, Paul CrockerAbstractA Golden Retriever cross was presented with a four week history of violent sneezing and licking at the nasal planum. Nasal mycosis was diagnosed and Aspergillus sp. presumed the causative agent, until culture, PCR and DNA sequencing showed that Scedosporium apiospermum, an uncommonly diagnosed, yet emerging, fungal pathogen, was the agent responsible. Debridement of the fungal plaques and systemic itraconazole therapy resulted in complete resolution...
Source: Medical Mycology Case Reports - August 8, 2018 Category: Biology Source Type: research

Aspergillus flavus endocarditis in an immunocompetent child. case report
We present an immunocompetent 7- year-old female with a history of multiple cardiac surgeries who developed fungal endocarditis due to Aspergillus flavus. The histology study showed liquefactive necrosis and septate hyphae of Aspergillus sp type. The clinical outcome was favorable and the ambulatory follow-up after 12 months showed no new complications. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - August 8, 2018 Category: Biology Source Type: research

Disseminated angioinvasive basidiobolomycosis with a favourable outcome
We report this case to remind physicians and surgeons to consider this diagnosis in patients from endemic area presenting with such conditions. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - August 8, 2018 Category: Biology Source Type: research

Kodamaea ohmeri fungemia in severe burn: case study and literature review
Publication date: Available online 20 July 2018Source: Medical Mycology Case ReportsAuthor(s): Ayaka Tashiro, Takahito Nei, Ryoji Sugimoto, Akiko Watanabe, Jun Hagiwara, Toru Takiguchi, Hiroyuki Yokota, Katsuhiko KameiAbstractKodamaea ohmeri is a relatively rare yeast isolated form clinical specimens, and it is known to be a causative fungus of severe invasive infectious diseases in immunocompromised hosts. Herein, we describe fungemia due to K. ohmeri in a patient with a severe extended burn. The isolate was obtained from not only blood specimens but also skin lesions. We should be aware of risk for fungemia including K. ...
Source: Medical Mycology Case Reports - July 20, 2018 Category: Biology Source Type: research

Cutaneotrichosporon (Cryptococcus) cyanovorans, a basidiomycetous yeast, isolated from the airways of cystic fibrosis patients
Publication date: Available online 18 July 2018Source: Medical Mycology Case ReportsAuthor(s): Tjomme van der Bruggen, Anna Kolecka, Bart Theelen, Johanna M. Kwakkel-van Erp, Bert Arets, Teun BoekhoutAbstractCystic fibrosis (CF) patients are colonized with a multitude of bacteria and fungi. From respiratory samples of two CF patients in our institute, a difficult to identify yeast was isolated repeatedly. This yeast was eventually identified as Cutaneotrichosporon (Cryptococcus) cyanovorans by internal transcribed spacer (ITS) and ribosomal large subunit (LSU) sequencing. C. cyanovorans is a basidiomycetous yeast originall...
Source: Medical Mycology Case Reports - July 19, 2018 Category: Biology Source Type: research

Late-onset isavuconazole-induced liver injury
We report a case of late-onset DILI occurring after 11 months of isavuconazole therapy in a 55-year old man of Angolan descent on long-term antifungal therapy for the management of chronic pulmonary aspergillosis complicating previously treated pulmonary tuberculosis. The DILI could be described as idiosyncratic as it was not associated with high isavuconazole serum levels and his liver function tests returned to normal following treatment discontinuation. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 19, 2018 Category: Biology Source Type: research

Aspergillus Hepatic Artery Thrombosis in Liver Transplantation
We present the first cirrhotic patient who underwent liver transplantation (LT) and presented a hepatic artery thrombosis of the graft due to Aspergillus fumigatus, within the first month of LT. This culminated in graft loss, re-transplant with multiple biliary and infectious complications. To our knowledge, this is a case report of an early hepatic artery thrombosis due to Aspergillus fumigatus in an infection-free patient. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 19, 2018 Category: Biology Source Type: research

Donor-derived invasive aspergillosis after kidney transplant
We report 2 cases of kidney transplant recipients who acquired aspergillosis from a single donor. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 18, 2018 Category: Biology Source Type: research

Bilateral Candida keratitis in an HIV patient with asymptomatic genitourinary Candidiasis in Uganda
Publication date: Available online 17 July 2018Source: Medical Mycology Case ReportsAuthor(s): Simon Arunga, Teddy Kwaga, Astrid Leck, Victor H Hu, Matthew J BurtonAbstractA 35-year-old male presented with Candida keratitis in the left eye. He was HIV positive with a CD4 of 352 cells/µL. The eye quickly deteriorated, despite intensive antifungal treatment and was eviscerated. Five months later, he re-presented with Candida keratitis in his right eye. A focal source of Candida infection was suspected and a urine culture identified Candida spp, despite being asymptomatic for genitourinary candidiasis. He was subsequent...
Source: Medical Mycology Case Reports - July 17, 2018 Category: Biology Source Type: research

Disseminated Cryptococcosis in a HIV-Negative Patient: Case Report of a Newly Diagnosed Hypertensive Adult Presenting with Hemiparesis
We report a case of disseminated cryptococcosis in a 42-year old immunocompetent female. Prior to admission at Bugando Medical Centre, the patient was attended at three hospitals for hypertension and clinically diagnosed malaria. Following diagnosis of disseminated Cryptococcus at our center, she was successfully treated with fluconazole but remained with visual loss. Blood cultures should be considered in the management of any adult presenting with fever to enable early detection of the least expected differentials like in this case. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 13, 2018 Category: Biology Source Type: research

Triadelphia pulvinata: A rare invasive fungal infection in a diabetic patient
We report a case of Triadelphia pulvinata, a rare dematiaceous fungi causing invasive fungal infection in a 68 year old diabetic Iraqi female. The diagnosis was made by combining the phenotypic findings and genome sequencing. There are only 4 case reports in literature and this is probably the first from India which was treated by Liposomal Amphotericin B. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research

Long term survival of a dog with disseminated Aspergillus deflectus infection without definitive treatment
Publication date: Available online 10 July 2018Source: Medical Mycology Case ReportsAuthor(s): Peter F. Bennett, Jessica J. Talbot, Patricia Martin, Sarah E Kidd, Mariano Makara, Vanessa R. BarrsAbstractCanine disseminated fungal infection by Aspergillus species carries a guarded to grave prognosis as they often rapidly progress and are refractory to treatment with many euthanased soon after diagnosis. This case report describes a 2.5 year old female spayed German Shepherd Dog diagnosed with disseminated Aspergillus deflectus infection for which definitive treatment was declined by the owners. With only palliative manageme...
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research

Successful treatment of breakthrough disseminated Trichosporon asahii fungemia in a patient with acute myeloid leukemia receiving itraconazole prophylaxis
Publication date: June 2018Source: Medical Mycology Case Reports, Volume 20Author(s): Daiki Karigane, Masatoshi Sakurai, Emiko Matsuyama, Kentaro Ide, Sakiko Yamamoto-Takeuchi, Toyoko Inazumi, Sumiko KohashiAbstractWe encountered a case of a 73-year-old man with acute myeloid leukemia who developed Trichosporon asahii systemic infection while on itraconazole prophylaxis during severe neutropenia. Cryptococcal antigen was useful for diagnosis. Although itraconazole was ineffective in protecting against trichosporonosis, treatment was successful with voriconazole following liposomal amphotericin B. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research

Necrotizing fasciitis caused by Apophysomyces variabilis in an immunocompetent patient
Publication date: June 2018Source: Medical Mycology Case Reports, Volume 20Author(s): José Y. Rodríguez, Soraya E. Morales-López, Gerson J. Rodríguez, Carlos A. Álvarez-Moreno, Walter Ocampo, Martha L. Cepeda, Miguel A. Mora-ValderramaAbstractMucormycosis caused by Apophysomyces variabilis is rarely reported in humans. A case of A. variabilis infection in an immunocompetent men after friction burns in a car accident is described. The infection presented as a rapidly progressive necrotizing infection of the skin and soft tissue, which required extensive surgical debridement and total colon...
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research

Dermatophyte infection caused by Nannizzia gypsea: A rare case report from Madagascar
We report a rare case of dermatophyte infection of the glabrous skin (Tinea corporis) caused by Nannizzia gypsea (formerly Microsporum gypseum). A 22-year-old Malagasy female who reported close contact reportedly with cats, presented a single round lesion with a peripheral, active, squamous and pruriginous inflammatory bead. Morphologic species identification was confirmed by sequencing the internal transcribed spacer (ITS) region of the genome. Specific treatment with oral loratadine and topical miconazole cream was effective. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research

Diagnosis and management of a fatal case of sepsis caused by Candida parapsilosis sensu stricto in a neonate with omphalocele
We present a fatal case of persistent neonatal candidemia by Candida parapsilosis following omphalocele, without other anomalies. Despite an encouraging initial prognosis, after surgical correction and closure of the abdominal wall the case became difficult to treat, as in addition to the exposure of the patient to multiple risk factors for candidemia, antifungal therapy apparently was not adequate. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research

Hemophagocytic lymphohistiocytosis (HLH) secondary to disseminated histoplasmosis in the setting of Acquired Immunodeficiency Syndrome (AIDS)
We present a case of a middle-aged male with AIDS and renal failure, who developed HLH secondary to disseminated histoplasmosis. Etoposide chemotherapy as recommended by the HLH 2004 Guidelines was deferred and treatment focused instead on anti-fungal therapy. Anti-retroviral therapy followed thereafter. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research

Mould meningitis associated with intravenous drug use
We present a rare case of mould meningitis, ventriculitis and subependymal nodules in an immunocompetent patient, having likely seeded the meninges and ventricular system through intravenous drug use. The causative mould remains undetermined. The case highlights the poor sensitivity of CSF culture and the need to consider surgical biopsy where there is diagnostic difficulty and fungal infection is being considered. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research

Acute paracoccidioidomycosis with duodenal and cutaneous involvement and obstructive jaundice
We report a case of PCM with duodenal and cutaneous involvement simulating cholangitis that was initially misdiagnosed as a lymphoproliferative disease. Clinicians should consider acute paracoccidioidomycosis in the differential diagnosis of jaundice and/or signs/symptoms of cholangitis developing in young patients from paracoccidioidomycosis endemic regions. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research

Case of Scedosporium aurantiacum infection detected in a subcutaneous abscess
Publication date: June 2018Source: Medical Mycology Case Reports, Volume 20Author(s): Makoto Kondo, Hiroyuki Goto, Keiichi YamanakaAbstractThis is the case report of a Scedosporium aurantiacum infection in a subcutaneous abscess. The patient had underlying diabetes and malignant lymphoma. Scedosporium species occur widely in nature and are increasingly recognized as pathologies under specific conditions, such as in immunocompromised hosts. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research

Tracheal, laryngeal and pulmonary mucormycosis followed by organizing pneumonia in a patient with Adult Onset Still's Disease
We report a case of tracheal, laryngeal and pulmonary mucormycosis in a patient receiving immunosuppressive medication for an autoinflammatory fever syndrome. Mucormycosis was confirmed by histopathology from tracheal specimens and molecular evidence of Lichtheimia.A surgical approach was not possible because of the multifocal disease pattern and the extent of tracheal involvement. The patient was successfully treated with liposomal amphotericin B followed by posaconazole maintenance therapy. After 9 months, recurrent pulmonary mucormycosis was suspected but emerged as organizing pneumonia without evidence of active fungal...
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research

Late presentation of Pneumocystis jirovecii pneumonia after renal transplant: A case report
We report a rare case of Pneumocystis jirovecii pneumonia in a renal transplant recipient only on maintenance immunosuppression eleven years after transplant without concomitant CMV infection or recent episodes of graft rejection. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research

Differential distribution patterns of Fonsecaea agents of chromoblastomycosis, exemplified by the first case due to F. monophora from Argentina
Publication date: June 2018Source: Medical Mycology Case Reports, Volume 20Author(s): Marcelo Label, Luciana C. Karayan, Sybren De Hoog, Javier Afeltra, Togo Bustamante, Roxana G. VitaleAbstractChromoblastomycosis is a mutilating infection of the skin and subcutaneous tissues caused by melanized fungi belonging to the order Chaetothyriales. Proven cases of the main agent, Fonsecaea pedrosoi are mainly limited to (sub)tropical, humid climates of Latin and Central America and the Caribbean. Fonsecaea monophora has a global distribution along the equator. Cases outside the (sub)tropics have thus far mostly been considered to ...
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research

Acute fulminant invasive pulmonary aspergillosis in an immunocompetent host: An autopsy case report
Publication date: June 2018Source: Medical Mycology Case Reports, Volume 20Author(s): Yuuki Ohara, Takahiko Ito, Makoto Ito, Kyoko Yamashita, Shinya ToyokuniAbstractA 62-year-old previously healthy male who was a welder/smoker/drinker was admitted to Kani Tono Hospital for severe hypoxemia (Day 0). Initial physical and radiological examinations suggested an acute exacerbation of chronic obstructive pulmonary disease. However, respiratory failure developed rapidly, and he died on Day + 4. Aspergillus fumigatus was identified after his death, and he was diagnosed with invasive pulmonary aspergillosis. The clinical and path...
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research

Severe acute respiratory distress syndrome in a liver transplant patient
Publication date: September 2018Source: Medical Mycology Case Reports, Volume 21Author(s): Nicholas M. Moore., Laurie A. ProiaAbstractThis case report presents a 46-year old man with a failed liver transplant who presented with malaise and dyspnea. Imaging studies revealed diffuse reticulonodular infiltrates and innumerable miliary nodules and a left upper lobe consolidative mass. Examination of bronchoalveolar lavage fluid demonstrated yeast cells with broad-based budding. He was diagnosed with pulmonary blastomycosis and started therapy with liposomal amphotericin. In spite of therapy, he clinically worsened, developing ...
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research

Microbiological and immunological characteristics of a lethal pulmonary Aspergillus niger infection in a non-neutropenic patient
Publication date: September 2018Source: Medical Mycology Case Reports, Volume 21Author(s): Jessica D. Workum, Suzanne W. de Jong, Mark S. Gresnigt, Katharina L. Becker, Peter Pickkers, Frank L. van de Veerdonk, Yvonne F. Heijdra, Eva KolwijckAbstractInvasive pulmonary aspergillosis is increasingly described in non-neutropenic patients, such as patients with COPD receiving corticosteroids and the critically ill. Here, we present a case of a lethal pulmonary Aspergillus niger infection in a COPD patient. Immunological tests showed an impaired innate and adaptive immune response to Aspergillus. A history of COPD, unresponsive...
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research

Two cases of fungal keratitis caused by Metarhizium anisopliae
We present two cases of keratitis due to Metarhizium anisopliae in geographically separated areas of the United States. The isolates were microscopically similar but morphologically different and were identified by ribosomal DNA sequencing. Both isolates had low minimum inhibitory concentration (MIC) values to caspofungin and micafungin, but high MIC values to amphotericin B. The morphologic and antifungal susceptibility differences between the two isolates indicate possible polyphylogeny of the group. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research

Invasive pulmonary mucormycosis and aspergillosis in a patient with decompensated hepatic cirrhosis
This report also highlights the first non-diabetic case of invasive pulmonary mucormycosis with decompensated hepatic cirrhosis. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research

Subcutaneous abscesses caused by Trichophyton rubrum in the unilateral groin of an immunocompromised patient: A case report
Publication date: September 2018Source: Medical Mycology Case Reports, Volume 21Author(s): Utako Okata-Karigane, Yasuki Hata, Emiko Watanabe-Okada, Shunichi Miyakawa, Michi Ota, Yutaka Uzawa, Shigekazu Iguchi, Atsushi Yoshida, Ken KikuchiAbstractA 60-year-old Japanese man presented with multiple subcutaneous nodules in his left groin. Histologically, the nodules consisted of suppurative granulomas and abscesses not involving the hair follicles. Trichophyton rubrum TWCC57922 was detected by fungal culture and polymerase chain reaction (PCR) sequencing of the rDNA genes. We diagnosed these nodules as deeper dermal dermatophy...
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research