Preventing prosthesis-patient mismatch: With the correct valve, with a correct formula, or with both?

We read with great interest the article of Sabik and colleagues1 reporting 1-year outcomes with a novel stented bovine pericardial aortic bioprosthesis (PERIGON pivotal trial). It is striking that they report a 1-year prosthesis-patient mismatch (PPM) rate of 75.5%, with a severe PPM rate of 30.3%. Considering the negative impact of PPM on postoperative left ventricular mass regression, functional improvement and quality of life, heart failure, and long-term survival after aortic valve replacement,2 this high rate of PPM may pose a problem for the widespread use of this novel bioprosthesis.
Source: The Journal of Thoracic and Cardiovascular Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Adult: Aortic Valve: Letter to the Editor Source Type: research