Triple negative breast cancers express receptors for LHRH and are potential therapeutic targets for cytotoxic LHRH-analogs, AEZS 108 and AEZS 125

Conclusion: The current study confirms that LHRH-receptors are expressed by a significant proportion of TNBC and can be successfully used as homing sites for cytotoxic analogs of LHRH, such as AEZS-108 and AEZS-125.

http://www.biomedcentral.com/1471-2407/14/847

Source: BMC Cancer - November 19, 2014 Category: Cancer & Oncology Authors: Stephan SeitzStefan BuchholzAndrew SchallyFlorian WeberMonika Klinkhammer-SchalkeElisabeth InwaldRoberto PerezFerenc RickLuca SzalontayFlorian HohlaSabine SegererChui KwokOlaf OrtmannJörg Engel Source Type: research