Adult Cord Blood Transplantation (CBT) Recipients Have a High Incidence of Early Acute Kidney Injury (AKI) and AKI Increases Long-Term Chronic Kidney Disease (CKD) Risk

While adult double unit CBT (dCBT) has disease-free survival comparable to that of HLA-matched adult donor allografts, frequent patient (pt) comorbidities combined with chemotherapy/TBI& cyclosporine-A (CSA) contribute to AKI risk. Using KDIGO criteria, we analyzed renal injury incidence& risk factors in adults undergoing dCBT.

Source: Biology of Blood and Marrow Transplantation - January 31, 2019 Category: Hematology Authors: Victoria Gutgarts, Junting Zheng, Ioannis Politikos, Sean M. Devlin, Molly A. Maloy, Sergio A. Giralt, Michael Scordo, Valkal Bhatt, Ilya Glezerman, Edgar A. Jaimes, Muthukumar Thangamani, Insara Jaffer Sathick, Juliet N. Barker Tags: 175 Source Type: research