Invasive and Allergic Complications Due to Aspergillus fumigatus in Allogeneic Hematopoietic Cell Transplantation (HCT) Primary Immunodeficiency (PID) Patients

Invasive aspergillosis may complicate up to 23% of HCT. Three patients with predispositions to infection with Aspergillus pre-transplant underwent reduced intensity conditioning HCT for unrelated PIDs: hypomorphic IL2R- γ deficiency (36 y/o man, P1), STAT3 mutated Hyper IgE syndrome (7 y/o girl, P2), and EBV-associated lymphoproliferative disease with mutated IκBα (30 y/o woman, P3).
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Tags: 532 Source Type: research