Is hereditary angioedema related to an increased risk of atherosclerosis?

We paid close attention in reading the interesting paper by Nebenf ührer et al,1 whose findings excluded the presence of endothelial dysfunction in hereditary angioedema with C1 inhibitor deficiency (C1-INH-HAE) patients. Their results are opposite of those recently published by our research group.2 Because the issue is important, impaired endothelial function be ing correlated with future occurrences of adverse cardiovascular events and cardiac death,3 we think that a few points should be worthy of debate.

Source: Annals of Allergy, Asthma and Immunology - January 30, 2019 Category: Allergy & Immunology Authors: Pier Paolo Bassareo, Davide Firinu, Stefano Del Giacco Tags: Correspondence Source Type: research