Role of Platelet-Rich Plasma in Articular Cartilage Injury and Disease

This article provides an overview of the basic science behind the use of PRP in the treatment of cartilage injury and disease. Both initial and current examples of the use of intra-articular PRP in clinical human studies are provided. These include the use of PRP either alone or as an augmentation device with various other procedures, including arthroscopic microfracture and cell-free resorbable polyglycolic acid-hyaluronan implantation. Finally, the authors describe some of the potential future roles of PRP in clinical settings based on recent literature. These include Achilles tendon rupture, chronic tendinosis, chronic rotator cuff tendinopathy or tearing, muscle injury, and meniscal repair.[...]Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals:Table of contents  |  Abstract  |  Full text
Source: Journal of Knee Surgery - Category: Orthopaedics Authors: Tags: Special Focus Section Source Type: research

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ConclusionThis study demonstrated that the nearer the tibial tunnel position to the anatomic attachment of the MM posterior root, the more effective the reduction in MMPE at 90 ° knee flexion. Our results emphasize that an anatomic tibial tunnel should be created in the MM posterior root to improve the postoperative MMPE and protect the articular cartilage in a knee flexion position. Placement of an anatomic tibial tunnel significantly improves the MMPE at 90° of knee fl exion after MM posterior root pullout repair.Level of evidenceIV.
Source: Knee Surgery, Sports Traumatology, Arthroscopy - Category: Orthopaedics Source Type: research
Publication date: May–June 2020Source: Revista Española de Cirugía Ortopédica y Traumatología (English Edition), Volume 64, Issue 3Author(s): M. Carabajal, G.J. Allende, J.J. Masquijo
Source: Revista Espanola de Cirugia Ortopedica y Traumatologia - Category: Orthopaedics Source Type: research
Conditions:   Suprascapular Nerve Block;   Axillary Nerve Block;   Dexmedetomidine;   Arthroscopic Rotator Cuff Repair;   Postoperative Pain;   Pain Related Cytokine Interventions:   Drug: Dexmedetomidine injection;   Drug: Saline injection Sponsors:   Chuncheon Sacred Heart Hospital;   Hallym University Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Authors: Sheean AJ, Kibler WB, Conway J, Bradley JP Abstract Posterior glenohumeral instability in overhead athletes presents a unique set of challenges for both diagnosis and treatment. Although a great deal of attention has been focused on the management of injuries to the biceps-labrum complex and rotator cuff in throwers, comparatively less has been written about posterior glenohumeral instability within this unique cohort. Historically, posterior instability has been observed secondary to either acute trauma or repetitive microtrauma, usually among collision athletes, weight lifters, and rowers. However, poste...
Source: The Journal of the American Academy of Orthopaedic Surgeons - Category: Orthopaedics Tags: J Am Acad Orthop Surg Source Type: research
ConclusionThe SST, ASES score, and UCLA scale evaluated at 2  years postoperatively have substantial ceiling effects showing that the proportion of patients with the maximum possible score is>  20%, and the standardised distance is
Source: Knee Surgery, Sports Traumatology, Arthroscopy - Category: Orthopaedics Source Type: research
Condition:   Biceps Tendon Lesion Interventions:   Diagnostic Test: Measurement of Muscle strength using a dynamometer;   Diagnostic Test: Range of motion clinical measurement (shoulder and elbow);   Diagnostic Test: Electromyography (EMG) Sponsor:   University Hospital, Basel, Switzerland Enrolling by invitation
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
In this study, the authors compared whether rotator cuff tears with knotted or knotless transosseous equivalent affected re-tear rates. Based on their systematic review, the authors concluded that the application of the above two transosseous equivalents did not affect re-tears of the rotator cuff.
Source: Arthroscopy - Journal of Arthroscopic and Related Surgery - Category: Surgery Authors: Tags: Letter to the Editor Source Type: research
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